56857-47-7 Usage
Uses
Used in Pharmaceutical Industry:
L-Alanine, N-(carboxymethyl)(9CI) is used as an intermediate in the synthesis of peptides and proteins for the development of pharmaceuticals. Its role in the synthesis process is crucial for creating complex biologically active molecules that can be used as therapeutic agents.
Used in Food Additive Industry:
In the food additive industry, L-Alanine, N-(carboxymethyl)(9CI) is used as a component in the production of flavor enhancers and other additives that improve the taste and quality of food products.
Used in Drug Delivery Systems:
L-Alanine, N-(carboxymethyl)(9CI) is employed in drug delivery systems to improve the solubility, stability, and bioavailability of pharmaceutical compounds, thereby enhancing their therapeutic efficacy.
Used in Metal-Ion Coordination Chemistry:
As a chelating agent, L-Alanine, N-(carboxymethyl)(9CI) is used in metal-ion coordination chemistry to form stable complexes with metal ions, which can be applied in various analytical and industrial processes.
Used in Laboratory Research:
L-Alanine, N-(carboxymethyl)(9CI) serves as a biochemical reagent in laboratory research, where it is used for studying the structure and function of proteins and peptides, as well as for the development of new biochemical assays and techniques.
Used in Industrial Processes:
In various industrial processes, L-Alanine, N-(carboxymethyl)(9CI) is utilized as a component in the production of chemicals, materials, and other products, contributing to the efficiency and effectiveness of these processes.
Check Digit Verification of cas no
The CAS Registry Mumber 56857-47-7 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,6,8,5 and 7 respectively; the second part has 2 digits, 4 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 56857-47:
(7*5)+(6*6)+(5*8)+(4*5)+(3*7)+(2*4)+(1*7)=167
167 % 10 = 7
So 56857-47-7 is a valid CAS Registry Number.
56857-47-7Relevant academic research and scientific papers
Iminodiacetic Acid as a Novel Metal-Binding Pharmacophore for New Delhi Metallo-β-lactamase Inhibitor Development
Chen, Allie Y.,Thomas, Caitlyn A.,Thomas, Pei W.,Yang, Kundi,Cheng, Zishuo,Fast, Walter,Crowder, Michael W.,Cohen, Seth M.
supporting information, p. 1272 - 1282 (2020/05/25)
The fungal natural product aspergillomarasmine A (AMA) has been identified as a noncompetitive inhibitor of New Delhi metallo-β-lactamase-1 (NDM-1) that inhibits by removing ZnII from the active-site. The nonselective metal-chelating properties and difficult synthesis and derivatization of AMA have hindered the development of this scaffold into a potent and selective inhibitor of NDM-1. Iminodiacetic acid (IDA) has been identified as the metal-binding pharmacophore (MBP) core of AMA that can be leveraged for inhibitor development. Herein, we report the use of IDA for fragment-based drug discovery (FBDD) of NDM-1 inhibitors. IDA (IC50=120 μM) was developed into inhibitor 23 f (IC50=8.6 μM, Ki=2.6 μM), which formed a ternary complex with NDM-1, as evidenced by protein thermal-shift and native-state electrospray ionization mass spectrometry (ESI-MS) experiments. Combining mechanistic analysis with inhibitor derivatization, the use of IDA as an alternative AMA scaffold for NDM-1 inhibitor development is detailed.
