568588-47-6

Basic information

• Product Name: Cyclohexanecarboxylic acid, 2-[[[(1S)-2-hydroxy-1-phenylethyl]amino]carbonyl]-, methyl ester, (1S,2S)-
• CAS NO: 568588-47-6
• Molecular Formula: C17H23NO4
• Molecular Weight: 305.374
• Mol File: 568588-47-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: Cyclohexanecarboxylic acid, 2-[[[(1S)-2-hydroxy-1-phenylethyl]amino]carbonyl]-, methyl ester, (1S,2S)-(CAS DataBase Reference)
• NIST Chemistry Reference: Cyclohexanecarboxylic acid, 2-[[[(1S)-2-hydroxy-1-phenylethyl]amino]carbonyl]-, methyl ester, (1S,2S)-(568588-47-6)
• EPA Substance Registry System: Cyclohexanecarboxylic acid, 2-[[[(1S)-2-hydroxy-1-phenylethyl]amino]carbonyl]-, methyl ester, (1S,2S)-(568588-47-6)

Safety Data

• Hazardous Substances Data: 568588-47-6(Hazardous Substances Data)

Upstream product

• 186581-53-3 diazomethane 
• 610-10-6 (1S,2S)-cyclohexane-1,2-dicarboxylic acid 
• 20989-17-7 (2S)-2-phenylglycinol 

Downstream Products

• 568588-59-0 (1S,2S)-2-((S)-4-Phenyl-4,5-dihydro-oxazol-2-yl)-cyclohexanecarboxylic acid ((S)-2-hydroxy-1-phenyl-ethyl)-amide 
• 568588-45-4 (S,S)-1,2-bis[(S)-(4-phenyl)-1,3-oxazolin-2-yl]cyclohexane 

Relevant articles and documents

Asymmetric cyclization-carbonylation of 2-propargyl-1,3-dione

The first example of asymmetric cyclization-carbonylation of 2-propargyl-1,3-dione 1 catalyzed by palladium(II) with chiral bisoxazolines (C.H.-BOX) was investigated. The use of bulky alcohols increased the ee of the products 2. The product 2d was converted into bicyclic enones 7 and 8, a useful intermediate for the synthesis of natural products.