5686-23-7Relevant academic research and scientific papers
SYNTHESIS OF DIPEPTIDES CONTAINING PROPARGYLGLYCINE AND 2-AMINOPIMELIC ACID
Auger, Genevieve,Heijenoort, Jean van,Blanot, Didier
, p. 729 - 734 (2007/10/02)
Two dipeptides containing antibacterial amino acids, 2-aminopimelic acid (Apm) and propargylglycine (Pra), were synthesized : L-Pra-ambo-Apm (1) and ambo-Apm-L-Pra (2). 1 was easily obtained from the protected derivative resulting from the coupling (carbo
Composition containing a penem or carbapenem antibiotic
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, (2008/06/13)
Administration of an N-acylated amino acid in association with a penem or carbapenem antibiotic relieves or eliminates the renal problems associated with administration of the antibiotic alone. The amino acid derivative and antibiotic may be formulated together as a composition or administered separately, either simultaneously or sequentially. The composition may be prepared by simple mixing.
