56872-64-1Relevant academic research and scientific papers
4-phenyl-4-oxo-butanoic acid derivatives with kynurenine-3-hydroxylase inhibiting activity
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, (2008/06/13)
4-phenyl-4-oxo-butanoic acid derivatives for use in the treatment of the human or animal body by therepy; particularly as kynurenine-3-hydroxylase inhibitors, in the prevention and/or treatment of a neurodegenerative disease wherein the inhibition of such an enyzme is needed. The present invention further comprises a selected class of the above mentioned 4-phenyl-4-oxo-butanoic acid derivatives, their pharmaceutically acceptable salts, a process for their preparation and pharmaceutical compositions containing them.
3-(3-(3-SUBSTITUTED AMINO-2-HYDROXYPROPOXY)PHENYL)-6-HYDRAZINO PYRIDAZINES AND THEIR USE AS VASODILATORS AND BETA-ADRENERGIC BLOCKING AGENTS
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, (2008/06/13)
The compounds are 3-(3-(3-substituted amino-2-hydroxypropoxy) phenyl)-6-hydrazino pyridazines which have β-adrenergic blocking and vasodilator activity.
6-(3-SUBSTITUTED AMINO-2-HYDROXYPROPOXYARYL)-4,5-DIHYDRO-3(2H)-PYRIDAZINONES
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, (2008/06/13)
The compounds are 6-(3-substituted amino-2-hydroxypropoxyaryl)-4,5-dihydro-3(2H)-pyridazinones which are β-adrenergic blocking agents.
