56875-38-8

Basic information

• Product Name: tetraethyl (1,3-phenylenebis(methylene))bis(phosphonate)
• Synonyms: tetraethyl (1,3-phenylenebis(methylene))bis(phosphonate);Diethyl 3-[(diethylphosphonomethyl)phenyl]methylphosphonate;1,3-bis(diethoxyphosphorylmethyl)benzene
• CAS NO: 56875-38-8
• Molecular Formula: C₁₆H₂₈O₆P₂
• Molecular Weight: 378.337442
• Mol File: 56875-38-8.mol
• Article Data: 13

Chemical Properties

• Appearance: /
• CAS DataBase Reference: tetraethyl (1,3-phenylenebis(methylene))bis(phosphonate)(CAS DataBase Reference)
• NIST Chemistry Reference: tetraethyl (1,3-phenylenebis(methylene))bis(phosphonate)(56875-38-8)
• EPA Substance Registry System: tetraethyl (1,3-phenylenebis(methylene))bis(phosphonate)(56875-38-8)

Safety Data

• Hazardous Substances Data: 56875-38-8(Hazardous Substances Data)

Upstream product

• 626-16-4 3-(chloromethyl)benzyl chloride 
• 122-52-1 triethyl phosphite 
• 626-15-3 1,3-bis-(bromomethyl)benzene 

Downstream Products

• 144052-40-4 meta-xylene-α,α'-diphosphonic acid 
• 1236355-57-9 (E,E)-3,5-bis(4'-methoxy-3'-methoxymethoxystyryl)benzene 
• 1396037-57-2 (E,E)-3,5-bis(4'-methoxymethoxy-3'-N,N-dimethylaminostyryl)benzene 
• 1396037-62-9 (E,E)-3,5-bis(3'-methoxymethoxy-4'-N,N-dimethylaminostyryl)benzene 
• 1396037-49-2 (E,E)-3,5-bis(3'-methoxy-4'-methoxymethoxystyryl)benzene 
• 849434-20-4 (E,E)-3,5-bis-(4'-hydroxy-3'-methoxystyryl)benzene 
• 1396037-45-8 (E,E)-3,5-bis(3'-methoxymethoxystyryl)benzene 
• 1396039-76-1 (E,E)-3,5-bis-(3'-hydroxystyryl)benzene 
• 1236355-33-1 (E,E)-3,5-bis-(3'-hydroxy-4'-methoxystyryl)benzene 
• 1725-76-4 (E,E)-1,3-distyrylbenzene 
• 114468-34-7 1,1'-{1,3-phenylenebis[(E)-ethene-2,1-diyl]}bis(3,4-dimethoxybenzene) 
• 1202480-76-9 (E,E)-3,5-bis-(4'-hydroxystyryl)benzene 
• 1256334-10-7 (E,E)-3,5-bis(4'-methoxymethoxystyryl)benzene 
• 1240737-75-0 E,E-1,3-bis(4-cyanostyryl)benzene 

Relevant articles and documents

BIS-BUTADIENE DERIVATIVE AND ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER

A bis-butadiene derivative is represented by general formula (1) shown below. In general formula (1), Ra, Rb, and Rc each represent, independently of one another, an alkyl group having a carbon number of at least 1 and no greater than 8 or an alkoxy group

PH-dependent syntheses, luminescence and magnetic properties of two-dimensional framework lanthanide 1,3-diarylphosphonate complexes

A series of novel organic-inorganic complexes based on trivalent lanthanides and 1,3-C6H4[CH2P(O)(OH) 2]2 (H4L) formulated as Ln(HL)(H 2O)2 (Ln = La, 1; Pr, 2; Nd, 3;

Phenolic bis-styrylbenzenes as β-amyloid binding ligands and free radical scavengers

Starting from bisphenolic bis-styrylbenzene DF-9 (4), β-amyloid (Aβ) binding affinity and specificity for phenolic bis-styrylbenzenes, monostyrylbenzenes, and alkyne controls were determined by fluorescence titration with β-amyloid peptide Aβ1-40 and a fluorescence assay using APP/PS1 transgenic mouse brain sections. Bis-styrylbenzene SAR is derived largely from work on symmetrical compounds. This study is the first to describe Aβ binding data for bis-styrylbenzenes unsymmetrical in the outer rings. With one exception, binding affinity and specificity were decreased by adding and/or changing the substitution pattern of phenol functional groups, changing the orientation about the central phenyl ring, replacing the alkene with alkyne bonds, or eliminating the central phenyl ring. The only compound with an Aβ binding affinity and specificity comparable to 4 was its 3-hydroxy regioisomer 8. Like 4, 8 crossed the blood-brain barrier and bound to Aβ plaques in vivo. By use of a DPPH assay, phenol functional groups with para orientations seem to be a necessary, but insufficient, criterion for good free radical scavenging properties in these compounds.