56881-08-4

Upstream product

• 87702-89-4 3-(1',1'-dimethylallyl)-7-(1'',1''-dimethylallyloxy)coumarin 
• 77796-42-0 3-(1,1-dimethylallyl)-7-butyryloxycoumarin 
• 135656-81-4 2-(2,4-Dihydroxy-benzyl)-3,3-dimethyl-pent-4-enoic acid methyl ester 
• 135656-80-3 2-(2,4-Bis-benzyloxy-benzyl)-3,3-dimethyl-pent-4-enoic acid methyl ester 
• 135656-77-8 2-(1,1-dimethylallyl)-2,3-dihydro-O-benzylcoumaric acid 
• 135672-43-4 2-(1,1-dimethylallyl)-2,3-dihydro-O-benzyl-p-benzyloxycoumaric acid 

Downstream Products

• 20958-63-8 3-(1',1'-dimethylallyl)herniarin 

Relevant academic research and scientific papers

An Improved Synthesis of 3-(1,1-Dimethylallyl)coumarins

The syntheses of several 3-(1,1-dimethylallyl)coumarins, simple or bearing additional furan or pyran rings is achieved starting from the corresponding C-3 unsubstituted derivatives.The key step involves Ireland-Claisen rearrangements of allyl esters.

A new and efficient route to 3-(1,1-dimethylallyl)coumarins

A new method for the synthesis of 3-(1,1-dimethylallyl)coumarins is described. The key step involves an Ireland-Claisen rearrangement of an allyl ester

Synthesis of 3-(1,1-Dimethylallyl)xanthyletin, 3-(1,1-Dimethylallyl)-8-(3,3-dimethylallyl)xanthyletin, Gravelliferone and dl-Chalepin

The synthesis of title compounds has been achieved from the key intermediate 3-(1,1-dimethylallyl)-7-hydroxycoumarin (7) which, in turn, is obtained by triple Claisen rearrangement of 7-(3,3-dimethylallyl)oxycoumarin (2) using butyric anhydride as the trapping reagent.

Synthesis of 3-(1,1-Dimethylallyl)xanthyletin

The structure of naturally occurring coumarin 3-(1,1-dimethylallyl)xanthyletin as 3-(1,1-dimethyl-2-propenyl)-8,8-dimethyl-2H,8H-benzodipyran-2-one (6) has been confirmed by synthesis.