56888-62-1

Basic information

• Product Name: 2-CYCLOHEXYL-THIAZOLIDINE-4-CARBOXYLIC ACID
• Synonyms: TIMTEC-BB SBB000551;2-CYCLOHEXYL-THIAZOLIDINE-4-CARBOXYLIC ACID;2-cyclohexyl-1,3-thiazolidin-3-ium-4-carboxylate
• CAS NO: 56888-62-1
• Molecular Formula: C₁₀H₁₇NO₂S
• Molecular Weight: 215.31
• Mol File: 56888-62-1.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2-CYCLOHEXYL-THIAZOLIDINE-4-CARBOXYLIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: 2-CYCLOHEXYL-THIAZOLIDINE-4-CARBOXYLIC ACID(56888-62-1)
• EPA Substance Registry System: 2-CYCLOHEXYL-THIAZOLIDINE-4-CARBOXYLIC ACID(56888-62-1)

Safety Data

• Hazard Codes: Xi
• HazardClass: IRRITANT
• Hazardous Substances Data: 56888-62-1(Hazardous Substances Data)

Usage

General Description

(2RS,4R)-2-cyclohexylthiazolidine-4-carboxylic acid is a chemical compound with a molecular formula C9H15NO2S. It is a thiazolidine derivative and carboxylic acid, featuring a cyclohexyl group. (2RS,4R)-2-cyclohexylthiazolidine-4-carboxylic acid has been studied for its potential pharmaceutical properties, including anti-diabetic and anti-inflammatory effects. It is also used as a building block in organic synthesis and can be found in various research and manufacturing applications. Additionally, (2RS,4R)-2-cyclohexylthiazolidine-4-carboxylic acid has been investigated for its potential use in the treatment or management of various health conditions.

Upstream product

• 52-89-1 l-cysteine hydrochloride 
• 2043-61-0 cyclohexanecarbaldehyde 
• 52-90-4 L-Cysteine 

Downstream Products

• 1029800-17-6 (R)-2-cyclohexyl-thiazolidine-3,4-dicarboxylic acid 3-benzyl ester 
• 1029800-19-8 (R)-2-oxazol-5-yl-thiazolidine-3,4-dicarboxylic acid 3-benzyl ester 
• 72679-04-0 (R)-2-Cyclohexyl-3-((S)-3-mercapto-2-methyl-propionyl)-thiazolidine-4-carboxylic acid 
• 72678-74-1 (4R)-3-<(2S)-S-benzoyl-3-mercapto-2-methylpropanoyl>-2-cyclohexyl-4-thiazolidinecarboxylic acid 

Relevant articles and documents

Discovery of cysteine and its derivatives as novel antiviral and antifungal agents

Based on the structure of the natural product cysteine, a series of thiazolidine-4-carboxylic acids were designed and synthesized. All target compounds bearing thiazolidine-4-carboxylic acid were characterized by1 H-NMR,13 C-NMR, and

Discovery of 2-arylthiazolidine-4-carboxylic acid amides as a new class of cytotoxic agents for prostate cancer

To improve the selectivity and antiproliferative activity of previously reported serine amide phosphates (SAPs), we designed a new series of 4-thiazolidinone amides, in which the 4-thiazolidinone moiety was introduced as a phosphate mimic. However, these 4-thiazolidinone derivatives demonstrated less cytotoxicity in prostate cancer cells despite improved selectivity over RH7777 cells. To further optimize the thiazolidinone analogues in terms of cytotoxicity and selectivity, we made closely related structural modifications, which led us to the discovery of a new class of 2-arylthiazolidine-4-carboxylic acid amides. These compounds were potent cytotoxic agents with IC50 values in the low micromolar concentration range and demonstrated enhanced selectivity in receptor-negative cells compared to SAPs and 4-thiazolidinone amides.