56900-73-3Relevant academic research and scientific papers
CRYSTAL AND MOLECULAR STRUCTURE OF 2-BENZOYL-5-PHENYLPYRROLE
Kharchenko, V. G.,Chalaya, S. N.,Struchkov, Yu. T.,Espenbetov, A. A.,Litvinov, O. V.,Komyagin, N. T.
, p. 1113 - 1116 (1984)
An X-ray diffraction investigation of 2-benzoyl-5-phenylpyrrole, whose molecules are combined as dimers in the crystals, has been carried out.The bond lengths and angles have been presented.
Cu-Catalyzed Cascade Cyclization of Ketoxime Acetates and Alkynals Enabling Synthesis of Acylpyrroles
Xu, Zhenhua,Xian, Ning,Chen, Hongbiao,Deng, Guo-Jun,Huang, Huawen
supporting information, p. 1175 - 1180 (2021/05/06)
A facile copper-based catalytic system has been developed to enable efficient cyclization of methylketoximes and alkynals. This protocol provides a viable entry to synthetically and pharmaceutically useful 2-acylpyrroles with a broad range of compatible functionalities. Mechanistically, a key acyl migration is probably involved that leads to the formation of N-acyl pyrroles or otherwise NH pyrroles by further hydrolysis. More importantly, the present reaction system also gives an opportunity to realize three-component pyrrole assembly by simple addition of carboxylic acid.
Transition metal-catalyzed synthesis of pyrroles from dienyl azides
Dong, Huijun,Shen, Meihua,Redford, Joanne E.,Stokes, Benjamin J.,Pumphrey, Ashley L.,Driver, Tom G.
, p. 5191 - 5194 (2008/09/17)
(Chemical Equation Presented) A range of 2,5-disubstituted and 2,4,5-trisubstituted pyrroles can be synthesized from dienyl azides at room temperature using catalytic amounts of Znl2 or Rh2(O 2CC3F7)4.
CYCLIZATION OF 2,4-DICHLORO-1,5-PENTANEDIONES WITH NUCLEOPHILIC REAGENTS
Litvinov, O. V.,Chalaya, S. N.,Kharchenko, V. G.
, p. 878 - 882 (2007/10/02)
The mechanism of reaction of 2,4-dichloro-1,5-pentanediones with ammonia has been studied.Intramolecular cyclization of the intermediate resulting from nucleophilic attack at the carbonyl group can occur in two ways, depending on the reaction conditions,
SYNTHESE DE PYRROLES ET D'OXAZOLES PAR PYROLYSE DE N-(HYDROXY-2' ETHYL) AMINO-3 PROPENOATE
Pale-Grosdemange, Catherine,Chuche, Josselin
, p. 3397 - 3414 (2007/10/02)
The gas phas pyrolysis of various N-(2'-hydroxyethyl)-3-amino propenoates 1-6 and N-(2'-hydroxy-2'-phenyl ethyl)-3-amino propanoate 7-9 at 390 deg C-420 deg C leads respectively to formylpyrroles 11-16 and benzoylpyrroles 17-19 and, in some cases, to substituted oxazoles 36-39.The results are best explained by the intermediate formation of a dicarbonyl derivative followed either by an intramolecular thermal crotonisation or a six ? electrocyclization of an azomethine ylide.
Eine bequeme Synthese von 2-Aroyl-5-arylpyrrolen
Messinger, Paul,Kunick, Conrad
, p. 213 - 214 (2007/10/02)
2-Aroyl-5-arylpyrroles are prepared in 20-60percent yields by cyclocondensation of 1,5-diaryl-2-methylsulfinyl-1,5-pentanediones with ammonium acetate in acetic acid.
REACTION OF α-α'-DICHLORO-SUBSTITUTED 1,5-DIKETONES WITH AMMONIA AND AMMONIUM ACETATE
Kharchenko, V. G.,Chalaya, S. N.,Litvinov, O. V.
, p. 291 - 293 (2007/10/02)
Under the influence of ammonia or ammonium acetate, α-α'-dichloro-substituted 1,5-diketones undergo heterocyclization to give β-chloropyridines or 2-benzoylpyrrole derivatives.The structure of the final product depends on the reagent and the character of
