Welcome to LookChem.com Sign In|Join Free
  • or
2-(thiophen-2-yl)-1H-indole-3-carbaldehyde is an organic compound characterized by a unique molecular structure that combines a thiophene ring with an indole nucleus. Thiophene, a heterocyclic compound with a sulfur atom in the ring, is fused to the indole, which itself is a bicyclic aromatic system containing a benzene ring fused to a pyrrole. The presence of the aldehyde functional group (-CHO) at the 3-position of the indole ring endows 2-(thiophen-2-yl)-1H-indole-3-carbaldehyde with reactivity typical of aldehydes, making it a valuable intermediate in the synthesis of various pharmaceuticals, agrochemicals, and other specialty chemicals. Its chemical properties, such as its ability to form Schiff bases and its potential for further functionalization, make it a versatile building block in organic synthesis.

5691-07-6

Post Buying Request

5691-07-6 Suppliers

Recommended suppliers

  • Product
  • FOB Price
  • Min.Order
  • Supply Ability
  • Supplier
  • Contact Supplier

5691-07-6 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 5691-07-6 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 5,6,9 and 1 respectively; the second part has 2 digits, 0 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 5691-07:
(6*5)+(5*6)+(4*9)+(3*1)+(2*0)+(1*7)=106
106 % 10 = 6
So 5691-07-6 is a valid CAS Registry Number.

5691-07-6Upstream product

5691-07-6Downstream Products

5691-07-6Relevant academic research and scientific papers

A copper(ii)-catalyzed annulative formylation of o-alkynylanilines with DMF: a single-step strategy for 3-formyl indoles

Ganesan, Balaji,Senadi, Gopal Chandru,Guo, Bing-Chun,Hung, Min-Yuan,Lin, Wei-Yu

, p. 40968 - 40973 (2018)

In this paper, a copper(ii)-catalyzed reaction of o-alkynylanilines with dimethylformamide (DMF) in the presence of oxygen has been developed for synthesizing multisubstituted 3-formyl indole scaffolds. This one-pot reaction proceeds through a cascade 5-endo-dig cyclization followed by formylation to construct 1,2-disubstituted 3-formyl indoles. The key aspects of this synthesis method are the broad substrate scope (with 38 examples), and well tolerating various functional groups. In addition, a detailed mechanism has been proposed, where DMF may serve as a carbon source for the in situ C3 formylation of the obtained indole derivatives.

Post a RFQ

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

1 Customer Service

What can I do for you?
Get Best Price

Get Best Price for 5691-07-6