56911-72-9Relevant academic research and scientific papers
CHEMICAL COMPOUNDS
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Paragraph 0286; 0291-0292, (2021/01/23)
The present disclosure describes novel compounds, or their pharmaceutically acceptable salts, pharmaceutical compositions containing them, and their medical uses. Compounds of the disclosure have activity as dual modulators of Janus kinase (JAK), alone, or in combination with one or more of an additional mechanism, including a tyrosine kinase, such as TrkA or Syk, and PDE4, and are useful in the in the treatment or control of inflammation, auto-immune diseases, cancer, and other disorders and indications where modulation of JAK would be desirable. Also described herein are methods of treating inflammation, auto-immune diseases, cancer, and other conditions susceptible to inhibition of JAK and PDE4 by administering a compound herein described.
Organic synthetics and their vermicidal properties. IV
Schroetter,Hoegel,Tschaepe
, p. 147 - 151 (2007/10/15)
Nuclear substituted 2 ethylphenol derivatives containing free, esterified or etherified hydroxyl groups were found to be very active against Ascaris suum in vitro. Their activity was similar to that of other phenols with known anthelmintic properties and their acute toxicity in mammals was very low. A series of 2 ethylphenol derivatives with free hydroxyl groups was found to be additionally effective against the fertilised eggs of Ascaris suum.
