56914-07-9Relevant academic research and scientific papers
Polycyclic Azines. III (1). Synthesis of 3-Aminoimidazopyridine Derivatives by Cyclodesulfurization of N'-Substituted-N-(2-pyridylmethyl)thioureas with Dicyclohexylcarbodiimide (2,3)
Bourdais, J.,Omar, A.-Mohsen M. E.
, p. 555 - 558 (2007/10/02)
A series of 3-substituted aminoimidazopyridine derivatives have been synthesized by cyclodesulfurization of a variety of N'-substituted-N-(2-pyridylmethyl)thioureas with dicyclohexylcarbodiimide (DCCD). 1H Nmr spectral analysis of all synthesized c
Substituted ureas and thioureas and pharmaceutical compositions thereof
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, (2008/06/13)
A method of improving the endogenous production of prostaglandins by a mammal is disclosed, which comprises administering to the mammal an effective amount of 1-pyridylalkyl-3-naphthyl-2(thio)ureas. Disclosed also are novel substituted 1-pyridylalkyl-3-naphthyl-2(thio)ureas and therapeutic compositions thereof which are useful in carrying out the method of the invention. Disclosed also are methods of treating mammals for clinical conditions responsive to prostaglandins, such as, for example, male infertility, epidermal injuries, atonic uterine bleeding, thromboembolic disease and like clinical conditions.
