56924-14-2Relevant academic research and scientific papers
Tandem aza-Michael-condensation-Aldol cyclization reaction: Approach to the construction of DE synthon of (±)-camptothecin
Chavan, Subhash P.,Dhawane, Abasaheb N.,Kalkote, Uttam R.
scheme or table, p. 2781 - 2784 (2009/04/21)
An efficient synthesis of the DE ring of camptothecin, employing a Reformatsky and a tandem one-pot, three-step transformation involving aza-Michael reaction, condensation with ethyl malonyl chloride followed by intramolecular 'aldol' reaction to furnish
A practical formal synthesis of camptothecin
Chavan, Subhash P.,Pathak, Ashok B.,Kalkote, Uttam R.
, p. 6561 - 6563 (2008/02/12)
The synthesis of the DE ring of camptothecin using simple and inexpensive starting materials, employing an addition elimination reaction and selective esterification of an aliphatic carboxylic acid as key steps is described.
