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1-METHYL-4,5,6,7-TETRAHYDRO-1H-PYRROLO[3,2-C]PYRIDINE, commonly referred to as THP, is a heterocyclic chemical compound characterized by a molecular formula of C8H12N2. It features a pyrrolidine ring fused to a pyridine ring, which endows it with unique structural and functional properties. THP is recognized for its versatility in the pharmaceutical and chemical industries, serving as a building block in the synthesis of bioactive compounds and exhibiting sedative and analgesic properties.

569351-26-4

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569351-26-4 Usage

Uses

Used in Pharmaceutical Industry:
1-METHYL-4,5,6,7-TETRAHYDRO-1H-PYRROLO[3,2-C]PYRIDINE is used as a building block for the synthesis of various pharmaceutical drugs due to its ability to contribute to the development of bioactive compounds.
Used in Pain Management:
1-METHYL-4,5,6,7-TETRAHYDRO-1H-PYRROLO[3,2-C]PYRIDINE is used as an analgesic agent for its potential role in pain management, offering a therapeutic option for patients requiring pain relief.
Used as a Central Nervous System Depressant:
1-METHYL-4,5,6,7-TETRAHYDRO-1H-PYRROLO[3,2-C]PYRIDINE is used as a sedative, contributing to its potential applications in the management of conditions that require central nervous system depression.
Used in Asymmetric Synthesis:
1-METHYL-4,5,6,7-TETRAHYDRO-1H-PYRROLO[3,2-C]PYRIDINE is used as a chiral auxiliary in asymmetric synthesis, playing a crucial role in the production of enantiomerically pure compounds, which are essential in various chemical and pharmaceutical applications.
Used in Metal-Catalyzed Reactions:
1-METHYL-4,5,6,7-TETRAHYDRO-1H-PYRROLO[3,2-C]PYRIDINE is studied for its potential as a ligand in metal-catalyzed reactions, highlighting its utility in catalytic processes that are vital for the synthesis of complex organic molecules.

Check Digit Verification of cas no

The CAS Registry Mumber 569351-26-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 5,6,9,3,5 and 1 respectively; the second part has 2 digits, 2 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 569351-26:
(8*5)+(7*6)+(6*9)+(5*3)+(4*5)+(3*1)+(2*2)+(1*6)=184
184 % 10 = 4
So 569351-26-4 is a valid CAS Registry Number.

569351-26-4SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 16, 2017

Revision Date: Aug 16, 2017

1.Identification

1.1 GHS Product identifier

Product name 1-methyl-4,5,6,7-tetrahydropyrrolo[3,2-c]pyridine

1.2 Other means of identification

Product number -
Other names -

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:569351-26-4 SDS

569351-26-4Downstream Products

569351-26-4Relevant articles and documents

Compound as potassium channel modulator

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Paragraph 0708; 0749; 0751; 0760; 0761, (2018/07/30)

The invention relates to a compound as a potassium channel modulator, which is a compound of a formula (I) or a pharmaceutically acceptable salt thereof. The compound or the pharmaceutically acceptable salt thereof is effective for curing and preventing diseases and symptoms influenced by the activity of potassium ion channels.

Binding of tetrahydrocarboline derivatives at human 5-HT5A receptors

Khorana, Nantaka,Smith, Carol,Herrick-Davis, Kathy,Purohit, Anil,Teitler, Milt,Grella, Brian,Dukat, Ma?gorzata,Glennon, Richard A.

, p. 3930 - 3937 (2007/10/03)

On the basis of an earlier finding that 5-methyl-5H-1,2,3,4-tetrahydropyrido[4,3-b]indole (5-methyl-1,2,3,4-tetrahydro-γ-carboline; 1) binds at murine 5-HT 5A receptors, preliminary structure-affinity studies were conducted. The present investigation extends these structure-affinity studies using human 5-HT5A receptors and examined additional analogues of 1. It was found (a) that there is little interspecies difference for the affinities of these compounds, (b) that an intact 1,2,3,4-tetrahydro-γ-carboline ring system seems optimal and an N2-(3-(substituted-phenoxy)propyl) moiety results in high affinity, (c) that structurally related 1,2,3,4-tetrahydro-β-carbolines also bind at 5-HT5A receptors, and (d) that all examined derivatives also possess affinity for 5-HT 2A receptors. Evidence is provided that 5-HT5A and 5-HT2A receptor affinities probably do not covary and that it might be possible, with continued investigation, to develop analogues with enhanced 5-HT5A selectivity.

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