5694-65-5

Usage

Uses

Used in Pharmaceutical Industry:
Dicyanoketene ethylene acetal is used as an intermediate for the synthesis of pharmaceuticals. Its reactivity allows for the creation of complex organic molecules that can be utilized in the development of new drugs.
Used in Agrochemical Industry:
In the agrochemical sector, dicyanoketene ethylene acetal is employed as a precursor in the production of various agrochemicals. Its ability to undergo multiple types of chemical reactions makes it a valuable component in the synthesis of pesticides and other agricultural chemicals.
Used in Fine Chemicals Production:
Dicyanoketene ethylene acetal is also used as an intermediate in the production of fine chemicals. Its versatility in chemical reactions enables the synthesis of specialty chemicals used in various industries, including fragrances, dyes, and other high-value products.
Safety Note:
Due to its reactivity and potential toxic effects, dicyanoketene ethylene acetal is considered potentially hazardous and should be handled with care in all applications.

InChI:InChI=1/C6H4N2O2/c7-3-5(4-8)6-9-1-2-10-6/h1-2H2

Upstream product

• 627-11-2 2-Chloroethyl chloroformate 
• 109-77-3 malononitrile 
• 107-21-1 ethylene glycol 
• 670-54-2 ethenetetracarbonitrile 

Downstream Products

• 168976-37-2 2-(cyan-(3'-(4''-chlor)phenyl-1',2',4'-oxadiazole-5'-yl))methylen-1,3-dioxolane 
• 168976-20-3 2-(cyan-(3'-phenyl-1',2',4'-oxadiazole-5'-yl))methylen-1,3-dioxolane 
• 168976-39-4 2-(cyan-(3'-(3''-nitro)phenyl-1',2',4'-oxadiazole-5'-yl))methylen-1,3-dioxolane 
• 168976-38-3 2-(cyan-(3'-(4''-nitro)phenyl-1',2',4'-oxadiazole-5'-yl))methylen-1,3-dioxolane 
• 168976-21-4 2-(cyan-(3'-(4''-methoxy)phenyl-1',2',4'-oxadiazole-5'-yl))methylen-1,3-dioxolane 
• 216447-96-0 4-amino-5-cyano-2-dimethylamino-6-ethoxypyrimidine 
• 98140-93-3 [amino-(2-hydroxy-ethoxy)-methylene]-malononitrile 
• 99420-70-9 5-amino-3-(2-hydroxy-ethoxy)-isoxazole-4-carbonitrile 
• 101893-42-9 S-(2-dicyanacetoxy-ethyl)-N,N'-diphenyl-isothiourea 
• 100725-02-8 4-amino-6-(2-hydroxy-ethoxy)-2-phenyl-pyrimidine-5-carbonitrile 

Relevant academic research and scientific papers

CDPK1 INHIBITORS, COMPOSITIONS, AND METHODS RELATED THERETO

The invention relates to inhibitors of calcium-dependent protein kinase 1 (CDPK1) and pharmaceutical preparations thereof. The invention further relates to methods of treatment of parasitic infections, such as T. gondii, P. falciparum, C. hominis, or C. parvum infections, using the novel inhibitors of the invention.

Optimizing Pyrazolopyrimidine Inhibitors of Calcium Dependent Protein Kinase 1 for Treatment of Acute and Chronic Toxoplasmosis

Calcium dependent protein kinase 1 (CDPK1) is an essential Ser/Thr kinase that controls invasion and egress by the protozoan parasite Toxoplasma gondii. The Gly gatekeeper of CDPK1 makes it exquisitely sensitive to inhibition by small molecule 1H-pyrazolo

CDPK1 INHIBITORS, COMPOSITIONS, AND METHODS RELATED THERETO

The invention relates to inhibitors of calcium-dependent protein kinase 1 (CDPK1 and pharmaceutical preparations thereof. The invention further relates to methods of treatment of parasitic infections, such as T. gondii, P. falciparum, C. hominis, or C. parvum infections, using the novel inhibitors of the invention.

CDPK1 INHIBITORS, COMPOSITIONS AND METHODS RELATED THERETO

The invention relates to inhibitors of calcium-dependent protein kinase 1 (CDPKl) and pharmaceutical preparations thereof. The invention further relates to methods of treatment of parasitic infections, such as T. gondii, T. cruzi, P. falciparum, T. brucei, or L. major infections, using the novel inhibitors of the invention.

A Facile Synthesis of Dialkoxycarbonylketene-, Dicyanoketene-, and Alkoxycarbonyl(cyano)ketene Ethylene Acetals

Dicyanoketene-, dialkoxycarbonylketene-, and alkoxycarbonyl(cyano)ketene ethylene acetals can be conveniently prepared by reaction of malononitrile, dialkyl malonates and alkyl cyanoacetates with 2-chloroethyl chloroformate.