5694-65-5

Basic information

• Product Name: DICYANOKETENE ETHYLENE ACETAL
• Synonyms: DICYANOKETENE ETHYLENE ACETAL;1,3-dioxolane-delta(sup2),alpha-malononitrile;2-dicyanomethylene-3-dioxolane;(1,3-Dioxolane-2-ylidene)malononitrile;2-(1,3-Dioxolane-2-ylidene)malononitrile;2-Dicyanomethylene-1,3-dioxolane;DCKEA
• CAS NO: 5694-65-5
• Molecular Formula: C₆H₄N₂O₂
• Molecular Weight: 136.11
• Mol File: 5694-65-5.mol
• Article Data: 5

Chemical Properties

• Melting Point: 113-114 °C(Solv: water (7732-18-5); ethanol (64-17-5))
• Boiling Point: 179.3°Cat760mmHg
• Flash Point: 69.1°C
• Appearance: /
• Density: 1.368g/cm³
• Vapor Pressure: 0.946mmHg at 25°C
• Refractive Index: 1.522
• CAS DataBase Reference: DICYANOKETENE ETHYLENE ACETAL(CAS DataBase Reference)
• NIST Chemistry Reference: DICYANOKETENE ETHYLENE ACETAL(5694-65-5)
• EPA Substance Registry System: DICYANOKETENE ETHYLENE ACETAL(5694-65-5)

Safety Data

• Hazardous Substances Data: 5694-65-5(Hazardous Substances Data)

Usage

General Description

Dicyanoketene ethylene acetal is a chemical compound with the molecular formula C7H6N2O2. It is a highly reactive compound that is used as a building block for the synthesis of various organic compounds. Dicyanoketene ethylene acetal is known for its ability to undergo a variety of chemical reactions, including addition, condensation, and hydrolysis. It is commonly used as an intermediate in the production of pharmaceuticals, agrochemicals, and other fine chemicals. DICYANOKETENE ETHYLENE ACETAL is considered to be potentially hazardous and should be handled with care due to its reactivity and potential toxic effects.

InChI:InChI=1/C6H4N2O2/c7-3-5(4-8)6-9-1-2-10-6/h1-2H2

Upstream product

• 107-21-1 ethylene glycol 
• 670-54-2 ethenetetracarbonitrile 
• 627-11-2 2-Chloroethyl chloroformate 
• 109-77-3 malononitrile 

Downstream Products

• 100725-02-8 4-amino-6-(2-hydroxy-ethoxy)-2-phenyl-pyrimidine-5-carbonitrile 
• 101893-42-9 S-(2-dicyanacetoxy-ethyl)-N,N'-diphenyl-isothiourea 
• 99420-70-9 5-amino-3-(2-hydroxy-ethoxy)-isoxazole-4-carbonitrile 
• 168976-37-2 2-(cyan-(3'-(4''-chlor)phenyl-1',2',4'-oxadiazole-5'-yl))methylen-1,3-dioxolane 
• 168976-20-3 2-(cyan-(3'-phenyl-1',2',4'-oxadiazole-5'-yl))methylen-1,3-dioxolane 
• 168976-39-4 2-(cyan-(3'-(3''-nitro)phenyl-1',2',4'-oxadiazole-5'-yl))methylen-1,3-dioxolane 
• 168976-38-3 2-(cyan-(3'-(4''-nitro)phenyl-1',2',4'-oxadiazole-5'-yl))methylen-1,3-dioxolane 
• 168976-21-4 2-(cyan-(3'-(4''-methoxy)phenyl-1',2',4'-oxadiazole-5'-yl))methylen-1,3-dioxolane 
• 216447-96-0 4-amino-5-cyano-2-dimethylamino-6-ethoxypyrimidine 
• 98140-93-3 [amino-(2-hydroxy-ethoxy)-methylene]-malononitrile 

Relevant articles and documents

CDPK1 INHIBITORS, COMPOSITIONS, AND METHODS RELATED THERETO

The invention relates to inhibitors of calcium-dependent protein kinase 1 (CDPK1) and pharmaceutical preparations thereof. The invention further relates to methods of treatment of parasitic infections, such as T. gondii, P. falciparum, C. hominis, or C. parvum infections, using the novel inhibitors of the invention.

CDPK1 INHIBITORS, COMPOSITIONS, AND METHODS RELATED THERETO

The invention relates to inhibitors of calcium-dependent protein kinase 1 (CDPK1 and pharmaceutical preparations thereof. The invention further relates to methods of treatment of parasitic infections, such as T. gondii, P. falciparum, C. hominis, or C. parvum infections, using the novel inhibitors of the invention.

A Facile Synthesis of Dialkoxycarbonylketene-, Dicyanoketene-, and Alkoxycarbonyl(cyano)ketene Ethylene Acetals

Dicyanoketene-, dialkoxycarbonylketene-, and alkoxycarbonyl(cyano)ketene ethylene acetals can be conveniently prepared by reaction of malononitrile, dialkyl malonates and alkyl cyanoacetates with 2-chloroethyl chloroformate.