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Usage

Uses

Used in Fragrance and Flavor Industry:
1-Phenylethyl (2E)-3-phenylprop-2-enoate is used as a fragrance and flavoring agent for its pleasant aroma, which is often described as floral, sweet, and slightly fruity. This makes it suitable for incorporation into various cosmetic and personal care products, as well as food and beverage flavorings.
Used in Pharmaceutical Industry:
1-Phenylethyl (2E)-3-phenylprop-2-enoate has potential applications in the pharmaceutical industry, particularly in the development of new medications and drug formulations. Its unique chemical structure may offer novel therapeutic properties and contribute to the advancement of pharmaceutical research and development.

Upstream product

• 98-85-1 1-Phenylethanol 
• 73789-34-1 cinnamic acid 4-chlorophenyl ester 
• 621-82-9 Cinnamic acid 

Relevant academic research and scientific papers

Convenient and Simple Esterification in Continuous-Flow Systems using g-DMAP

The utility and applicability of polyethylene-g-polyacrylic acid-immobilized dimethylaminopyridine (g-DMAP) as a catalyst in a continuous-flow system were investigated for decarboxylative esterification. High catalytic activity toward acylation was provided by g-DMAP containing a flexible grafted-polymer structure. During decarboxylation, carboxylic acids and alcohols were converted cleanly using di-tert-butyl dicarbonate (Boc2O) as a coupling reagent, which reduced by-products. In addition, the use of Boc2O resulted in the formation of tert-butyl esters. These esterifications dramatically reduced the reaction time under continuous-flow conditions, with a residence time of approximately 2 min. This highly efficient esterification procedure will provide more practical industrial applications.

Nucleophilic iron catalysis in transesterifications: Scope and limitations

Figure presented The ester bond is one of the most common structural motifs found in nature. Apart from the condensation between an acid and an alcohol, transesterifications represent another mechanistic alternative for the preparation of this compound class. The present paper summarizes our most recent investigations in this field, using nucleophilic iron complexes as catalysts for transesterifications under neutral conditions. This new type of metal catalyst complements the existing methodologies, which rely on Lewis acidic metal complexes. Investigations on scope and limitations, stereochemical course, and chemoselectivities will be presented.