569656-99-1

Upstream product

• 13565-09-8 4-bromocinnamoyl chloride 
• 569657-15-4 3-(4-bromo-phenyl)-N-methoxy-acrylamide 

Relevant academic research and scientific papers

Synthesis of spirodienones by intramolecular ipso-cyclization of N-methoxy-(4-halogenophenyl)amides using [hydroxy(tosyloxy)iodo]benzene in trifluoroethanol

Spirodienones bearing the 1-azaspiro[4.5]decane ring system have been synthesized from N-methoxy-(4-halogenophenyl)amides by the intramolecular ipso attack of a nitrenium ion generated with [hydroxy(tosyloxy)iodo]-benzene in trifluoroethanol.