569661-69-4

Upstream product

• 569661-65-0 2S-(2R,3R-bis-benzyloxy-5R-hydroxy-3R-methyl-tetrahydro-pyran-4R-yloxy)-7-[6R-(2,2-dimethyl-[1,3]dioxan-5-ylmethyl)-4S-methoxymethoxy-3R-(triethylsilanyloxoy)-tetrahydropyran-2R-yl]-5-methylhept-5E-enoic acid 
• 569661-02-5 7R,8R-dibenzyloxy-2S-{5-[6R-(2,2-dimethyl-[1,3]dioxan-5-ylmethyl)-4S-methoxymethoxy-3R-(triethylsilanyloxy)-tetrahydropyran-2R-yl]-3-methylpent-3E-enyl}-8R-methyltetrahydropyrano[3R,4R-b][1,4]dioxin-3-one 
• 80522-42-5 triisopropylsilyl trifluoromethanesulfonate 
• 569661-04-7 3S-(2R-3R-bis-benzyloxy-5-hydroxy-3R-methyltetrahydropyran-4R-yloxy)-6S-{2-[6R-(2,2-dimethyl-[1,3]dioxan-5-ylmethyl)-4S-methoxymethoxy-3R-(triethylsilanyloxy)-tetrahydropyran-2R-yl]-1R-iodoethyl}-6S-methyl-tetrahydropyran-2-one 

Downstream Products

• 569661-05-8 2S-[2R,3R-bisbenzyloxy-3R-methyl-5R-(triisopropyl-silanyloxy)-tetrahydropyran-4-yloxy]-4S-{3-[6R-(2,2-dimethyl-[1,3]dioxan-5-ylmethyl)-4S-methoxymethoxy-3R-(triethylsilanoxy)-tetrahydropyran-2R-yl]-2S-methyloxiranyl}butyric acid methyl ester 
• 569661-07-0 {5R,6R-dibenzyloxy-4R-[2R-(2,2-dimethyl-[1,3]dioxan-5-ylmethyl)-4S-methoxymethoxy-5aR-methyl-9R-vinyldodecahydro-1,5,10-trioxa-cyclohepta[b]naphthalen-8S-yloxy]-5R-methyltetrahydropyran-3R-yloxy}-triisopropylsilane 
• 569660-79-3 2R-(3S-{3S-[2R,3R-bis-benzyloxy-3R-methyl-5R-(triisopropylsilanyloxy)-tetrahydropyran-4R-yloxy]-hex-4Z-enyl}-3S-methyloxiranylmethyl)-6R-(2,2-dimethyl-[1,3]dioxan-5-ylmethyl)-4S-methoxymethoxytetrahydropyran-3R-ol 
• 569661-73-0 2S-[2R,3R-bisbenzyloxy-3R-methyl-5R-(triisopropylsilanyloxy)-tetrahydropyran-4-yloxy]-4-{3S-[6R-(2,2-dimethyl-[1,3]dioxan-5-ylmethyl)-4S-methoxymethoxy-3R-(triethylsilanoxy)-tetrahydropyran-2R-ylmethyl]-2S-methyl-oxiranyl}butyraldehyde 
• 569661-06-9 {5R,6R-dibenzyloxy-4R-[2R-(2,2-dimethyl-[1,3]dioxan-5-ylmethyl)-4S-methoxymethoxy-5aR-methyl-9S-(1S-phenylselanylethyl)-dodecahydro-1,5,10-trioxa-cyclohepta[b]naphthalen-8S-yloxy]-5R-methyltetrahydropyran-3R-yloxy}-triisopropyl-silane 
• 569661-71-8 2-(2,3-bis-benzyloxy-3-methyl-5-triisopropylsilanyloxy-tetrahydro-pyran-4-yloxy)-4-{3-[6-(2,2-dimethyl-[1,3]dioxan-5-ylmethyl)-4-methoxymethoxy-3-triethylsilanyloxy-tetrahydro-pyran-2-ylmethyl]-2-methyl-oxiranyl}-butan-1-ol 
• 569661-75-2 5-[6R-(3-{3S-[2R,3R-bis-benzyloxy-3R-methyl-5R-(triisopropylsilanyloxy)-tetrahydropyran-4R-yloxy]-hex-4Z-enyl}-3S-methyloxiranylmethyl)-4S-methoxymethyoxy-5R-(triethylsilanyloxy)-tetrahydropyran-2R-ylmethyl]-2,2-dimethyl-[1,3]dioxane 

Relevant academic research and scientific papers

A convergent total synthesis of hemibrevetoxin B

A convergent biomimetic synthesis of hemibrevetoxin B from d-glucal and d-arabinose utilizes an electrophile-promoted cascade anti-Baldwin cyclization of an epoxy alcohol. The epoxy alcohol arises from a palladium-catalyzed coupling of a highly functionalized organozinc compound and an alkenyl iodide, which serve as two chiral building blocks of similar size and complexity. This first successful implementation of a cascade epoxy alcohol cyclization for the synthesis of marine polycyclic ether toxins proceeds in 39 steps and 4% overall yield. Copyright