569671-24-5

Basic information

• Product Name: Benzeneacetamide, N-[(1S)-2-[(3S)-3-hydroxy-1-pyrrolidinyl]-1-phenylethyl]-4,5-dimethoxy-N -methyl-2-(4-morpholinylsulfonyl)-
• CAS NO: 569671-24-5
• Molecular Formula: C27H37N3O7S
• Molecular Weight: 547.673
• Mol File: 569671-24-5.mol

Chemical Properties

• CAS DataBase Reference: Benzeneacetamide, N-[(1S)-2-[(3S)-3-hydroxy-1-pyrrolidinyl]-1-phenylethyl]-4,5-dimethoxy-N -methyl-2-(4-morpholinylsulfonyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzeneacetamide, N-[(1S)-2-[(3S)-3-hydroxy-1-pyrrolidinyl]-1-phenylethyl]-4,5-dimethoxy-N -methyl-2-(4-morpholinylsulfonyl)-(569671-24-5)
• EPA Substance Registry System: Benzeneacetamide, N-[(1S)-2-[(3S)-3-hydroxy-1-pyrrolidinyl]-1-phenylethyl]-4,5-dimethoxy-N -methyl-2-(4-morpholinylsulfonyl)-(569671-24-5)

Safety Data

• Hazardous Substances Data: 569671-24-5(Hazardous Substances Data)

Upstream product

• 63212-44-2 [4,5-dimethoxy-2-(morpholine-4-sulfonyl)-phenyl]-acetic acid 
• 142773-73-7 N-Methyl-N[(1S)-1-phenyl-2-((3S)-3-hydroxypyrrolidine-1-yl)]ethane 

Relevant articles and documents

Use of receptor chimeras to identify small molecules with high affinity for the dynorphin A binding domain of the κ opioid receptor

A series of 2-substituted sulfamoyl arylacetamides of general structure 2 were prepared as potent κ opioid receptor agonists and the affinities of these compounds for opioid and chimeric receptors were compared with those of dynorphin A. Compounds 2e and 2i were identified as non-peptide small molecules that bound to chimeras 3 and 4 with high affinities similar to dynorphin A, resulting in Ki values of 1.5 and 1.2 nM and 1.3 and 2.2 nM, respectively.