569675-08-7Relevant academic research and scientific papers
Synthesis of new uracil non-nucleoside derivatives as potential inhibitors of HIV-1
El-Essawy, Farag A.,El-Brollosy, Nasser R.,Pedersen, Erik B.,Nielsen, Claus
, p. 213 - 217 (2007/10/03)
6-(2-Phenylethyl) and 6-cyclohexyl 5-cyanouracils (1a,b) were synthesized and reacted with chloromethyl ethyl ether, benzyl chloromethyl ether, chloromethyl methyl sulfide and (2-acetoxyethoxy)methyl bromide. New uracil analogues of (S)-DHPA were synthesized by reaction of compounds (1a,b) with ((S)-2,2-dimethyl-1,3-dioxolane-4-yl) alkyl p-toluenesulfonate.
