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9,9'-Di-O-(E)-feruloylsecoisolariciresinol, also known as DiFSA, is a natural phenolic compound and a lignan derivative found in various plant sources such as flaxseed and sesame seeds. It possesses potential antioxidant and anti-inflammatory properties, making it a subject of interest for its potential health benefits in the fields of medicine and nutrition.

56973-66-1

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56973-66-1 Usage

Uses

Used in Antioxidant Applications:
9,9'-Di-O-(E)-feruloylsecoisolariciresinol is used as an antioxidant agent for its ability to protect against oxidative stress, which is a key factor in the development of various diseases.
Used in Anti-Inflammatory Applications:
DiFSA is used as an anti-inflammatory agent due to its potential to reduce inflammation, which is implicated in numerous chronic conditions.
Used in Cancer Prevention and Treatment:
In the field of oncology, 9,9'-Di-O-(E)-feruloylsecoisolariciresinol is used as a potential anti-cancer agent for its possible role in the prevention and treatment of cancer, given its presence in natural sources and its studied effects.
Used in Neuroprotection:
9,9'-Di-O-(E)-feruloylsecoisolariciresinol is used as a neuroprotective agent for its potential to protect the nervous system, which could be beneficial in the context of neurodegenerative diseases.
Used in Pharmaceutical Industry:
DiFSA is used as a pharmaceutical candidate for its potential therapeutic effects in the development of new drugs targeting various diseases, leveraging its antioxidant and anti-inflammatory properties.
Used in Nutritional Supplements:
In the nutritional industry, 9,9'-Di-O-(E)-feruloylsecoisolariciresinol is used as an ingredient in supplements to enhance health and well-being by providing the benefits of its antioxidant and anti-inflammatory actions.

Check Digit Verification of cas no

The CAS Registry Mumber 56973-66-1 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,6,9,7 and 3 respectively; the second part has 2 digits, 6 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 56973-66:
(7*5)+(6*6)+(5*9)+(4*7)+(3*3)+(2*6)+(1*6)=171
171 % 10 = 1
So 56973-66-1 is a valid CAS Registry Number.

56973-66-1SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 16, 2017

Revision Date: Aug 16, 2017

1.Identification

1.1 GHS Product identifier

Product name (2R,3R)-2,3-Bis(4-hydroxy-3-methoxybenzyl)-1,4-butanediyl (2E,2'E )bis[3-(4-hydroxy-3-methoxyphenyl)acrylate]

1.2 Other means of identification

Product number -
Other names Octa-1,4-dien

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:56973-66-1 SDS

56973-66-1Downstream Products

56973-66-1Relevant academic research and scientific papers

Synthesis and evaluation of cytotoxic effects of hanultarin and its derivatives

Lee, Eunyoung,Jamal Ahamed,Kumar, Mahto Sanjeev,Rhee, Seog Woo,Moon, Surk-Sik,Hong, In Seok

, p. 6245 - 6248 (2011/12/02)

One of the known cytotoxic lignans is (-)-1-O-feruloyl-secoisolariciresinol designated as hanultarin, which was isolated from the seeds of Trichosanthes kirilowii. In this Letter, we described the first synthesis of 1-O-feruloyl-secoisolariciresinol, 1,4-O-diferuloyl-secoisolariceresinol and their analogues. The cytotoxicities of these compounds were evaluated against several cancer cell lines. Interestingly, we found that the feruloyl diester derivative of secoisolariciresinol was the most active cytotoxic compound against all the cancer cells tested in this experiment. The IC50 values of the1,4-O-diferuloyl-secoisolariceresinol were in the range of 7.1-9.8 lM except one cell line. In considering that both ferulic acid and secoisolariciresinol are commonly found in many plants and have no cytotoxicity, this finding is remarkable in that simple covalent bonds between the ferulic acid and secoisolariciresinol cause a cytotoxic effect.

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