56977-08-3

Usage

Uses

Used in Organic Synthesis:
1,5-Dibenzyl Glutarate is used as a chemical intermediate for the synthesis of a wide range of organic compounds. Its unique structure and properties make it a valuable building block in the development of pharmaceuticals, agrochemicals, and other specialty chemicals.
Used in Pharmaceutical Industry:
1,5-Dibenzyl Glutarate is used as a key component in the development of new drugs and therapeutic agents. Its versatility in organic synthesis allows for the creation of novel molecular structures with potential applications in treating various diseases and medical conditions.
Used in Agrochemical Industry:
In the agrochemical industry, 1,5-Dibenzyl Glutarate is used as a starting material for the synthesis of various pesticides, herbicides, and other crop protection agents. Its chemical properties make it suitable for the development of effective and environmentally friendly solutions for agricultural challenges.
Used in Specialty Chemicals:
1,5-Dibenzyl Glutarate is also used in the production of specialty chemicals, such as additives, coatings, and polymers. Its unique properties contribute to the development of innovative materials with specific applications in various industries, including automotive, electronics, and construction.

Upstream product

• 110-94-1 1,5-pentanedioic acid 
• 100-51-6 benzyl alcohol 
• 100-44-7 benzyl chloride 
• 538-60-3 dibenzyl hydrogen phosphite 
• 75-24-1 trimethylaluminum 
• 108-55-4 glutaric anhydride, 
• 201230-82-2 carbon monoxide 
• 107-18-6 allyl alcohol 
• 14593-43-2 benzyl allyl ether 

Downstream Products

• 173039-10-6 2-(phosphonomethyl)pentanedioic acid 
• 173039-05-9 dibenzyl 2-methylenepentanedioate 

Relevant academic research and scientific papers

ZWITTERIONIC CATALYSTS FOR (TRANS)ESTERIFICATION: APPLICATION IN FLUOROINDOLE-DERIVATIVES AND BIODIESEL SYNTHESIS

An amide/iminium zwitterion catalyst has a catalyst pocket size that promotes transesterification and dehydrative esterification. The amide/iminium zwitterions are easily prepared by reacting aziridines with aminopyridines. The reaction can be applied a wide variety of esterification processes including the large-scale synthesis of biodiesel. The amide/iminium zwitterions allow the avoidance of strongly basic or acidic condition and avoidance of metal contamination in the products. Reactions are carried out at ambient or only modestly elevated temperatures. The amide/iminium zwitterion catalyst is easily recycled and reactions proceed in high to quantitative yields.

Amide/Iminium Zwitterionic Catalysts for (Trans)esterification: Application in Biodiesel Synthesis

A class of zwitterionic organocatalysts based on an amide anion/iminium cation charge pair has been developed. The zwitterions are easily prepared by reacting aziridines with aminopyridines. They are catalytically applicable to transesterifications and dehydrative esterifications. Mechanistic studies reveal that the amide anion and iminium cation work synergistically in activating the reaction partners, with the iminium cationic moiety interacting with the carbonyl substrates through nonclassical hydrogen bonding. The reaction can be applied to large-scale synthesis of biodiesel under mild conditions.

PROCESS FOR DOUBLE CARBONYLATION OF ALLYL ALCOHOLS TO CORRESPONDING DIESTERS

The invention relates to a process for doubly carbonylating allyl alcohols to the corresponding diesters, wherein a linear or branched allyl alcohol is reacted with a linear or branched alkanol (alcohol) with supply of CO and in the presence of a catalytic system composed of a palladium complex and at least one organic phosphorus ligand and in the presence of a hydrogen halide selected from HCl, HBr and HI.

PROCESS FOR DOUBLE CARBONYLATION OF ALLYL ETHERS TO CORRESPONDING DIESTERS

The invention relates to a process for doubly carbonylating allyl ethers to the corresponding diesters, wherein a linear or branched allyl ether is reacted with a linear or branched alkanol (alcohol) with supply of CO and in the presence of a catalytic system composed of a palladium complex and at least one organic phosphorus ligand and in the presence of a hydrogen halide selected from HCl, HBr and HI.

Esterification of dicarboxylic acids with benzyl alcohol under the action of the microwave radiation

Reaction of dicarboxylic acid with benzyl alcohol under the microwave irradiation proceeds faster as compared to the thermal conditions. The main reaction products are alkyl dicarboxylates, and the monoester and dibenzyl ether are formed as the side products. A proposal about the nature of the nonthermal effect in the reactions stimulated by the microwave irradiation is considered.

CERTAIN PHOSPHONOMETHYL-PENTANEDIOIC ACID DERIVATIVES THEREOF

The present disclosure relates to dipeptidase inhibitors, and more particularly, to N-Acetylated α-Linked Acidic Dipeptidase (NAALADase) enzyme inhibitors which are proposed as novel agents for the treatment of prostate cancer. NAALADase is enzyme which i

SELECTIVE MONOETHERIFICATION AND MONOESTERIFICATION OF DIOLS AND DIACIDS UNDER PHASE-TRANSFER CONDITIONS

Research on the selectivity of etherification reactions of diols and esterification reactions of diacids by alkyl halides under phase-transfer catalysis has shown that under such conditions, selectivity of monoetherification increases in the order prim sec tert diols, though overall yield of monoether decreases from sec to tert diols.Monoesterification of diacids was accomplished with a high degree of selectivity.Optimal extraction of diols and diacids was found to correspond in general to chain lengths of around 5 carbons.This could mean that the complex formed between the catalyst and the anion to react is stabilized for certain carbon lengths by inner solvation in virtue of its spatial conformation.