56981-41-0

Usage

Uses

Used in Structure-Relationship Studies:
6-AMinohexyl β-D-Glucopyranoside is used as a compound in structure-relationship studies for its insulin-like activity. This application is significant as it helps researchers understand the relationship between the compound's structure and its ability to mimic or enhance insulin activity, which could be beneficial for the development of new drugs or therapies for conditions like diabetes.
Used in Drug Delivery Systems:
In the field of drug delivery, 6-AMinohexyl β-D-Glucopyranoside is used as a conjugate with magnetite nanoparticles (MNPs) to produce multifunctional HepG2 cancer cell-targeting agents. This application takes advantage of the compound's ability to bind specifically to certain types of cells, in this case, HepG2 cancer cells, allowing for targeted drug delivery. By attaching the compound to nanoparticles, researchers can potentially improve the efficacy and specificity of cancer treatments, reducing side effects and increasing the effectiveness of the therapy.

Upstream product

• 1266251-51-7 (6-azidohex-1-yl)-β-D-glucopyranoside 
• 2009-83-8 6-chloro-1-hexanol 
• 604-69-3 β-D-glucose pentaacetate 

Relevant academic research and scientific papers

Carbohydrates as potentially versatile core subcarriers for multivalent immunogens

Synthetic multivalent glycoclusters that carry carbohydrate antigen epitopes have been recognized as promising candidates for the development of carbohydrate based vaccines. Here we describe a convergent strategy for the synthesis of conjugation-ready multivalent glycoclusters using sugars as versatile core subcarriers. d-Glucose and gentiobiose were converted into poly-alkyne functionalized cores which were then decorated with an azide bearing model ligand d-glucose using click chemistry, to form structurally well-defined tetra- and heptavalent glycoclusters. Each cluster was conjugated to a model protein bovine serum albumin (BSA) by squaric acid chemistry. Carbohydrate clusters can be prepared in a variety of sizes and spatial arrangements by altering the structure and configuration of the core, depending on the mono-, or oligosaccharides used for their assembly. It is suggested that the use of carbohydrate as core subcarriers provides an opportunity to tailor the size and topology of antigens and modify multivalent presentation of immunogens in a way to optimize cluster effect for stronger immunoreactivity.

HEPARAN SULFATE GLYCOMIMETIC COMPOUNDS AND THEIR PHARMACEUTICAL AND COSMECEUTICAL USES

The invention relates to dendritic compounds, the use of these compounds as pharmaceuticals, pharmaceutical and cosmeceutical compositions containing the compounds, and methods of treating cancer, inflammation, diabetic nephropathy, neurodegenerative disorders, Niemann-Pick Type C disease, or dermatological conditions.