57012-17-6

Basic information

• Product Name: 4-methoxy-6-[(1E)-prop-1-en-1-yl]-5,6-dihydro-2H-pyran-2-one
• CAS NO: 57012-17-6
• Molecular Formula: C₉H₁₂O₃
• Molecular Weight: 168.1898
• Mol File: 57012-17-6.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 318.7°C at 760 mmHg
• Flash Point: 130.7°C
• Density: 1.08g/cm³
• Vapor Pressure: 0.000355mmHg at 25°C
• Refractive Index: 1.487
• CAS DataBase Reference: 4-methoxy-6-[(1E)-prop-1-en-1-yl]-5,6-dihydro-2H-pyran-2-one(CAS DataBase Reference)
• NIST Chemistry Reference: 4-methoxy-6-[(1E)-prop-1-en-1-yl]-5,6-dihydro-2H-pyran-2-one(57012-17-6)
• EPA Substance Registry System: 4-methoxy-6-[(1E)-prop-1-en-1-yl]-5,6-dihydro-2H-pyran-2-one(57012-17-6)

Safety Data

• Hazardous Substances Data: 57012-17-6(Hazardous Substances Data)

Upstream product

• 123-73-9 crotonaldehyde 
• 35471-25-1 ethyl γ-bromo-β-methoxy-cis-crotonate 

Relevant articles and documents

Efficient enantioselective hetero-diels-alder reaction of brassard's diene with aliphatic aldehydes: A one-step synthesis of (R)-(+)-kavain and (S)-(+)-dihydrokavain

An efficient catalytic asymmetric hetero-Diels-Alder reaction of Brassard's diene with aliphatic aldehydes was reported The catalyst which was generated from (R)-BINOL, Ti(i-PrO)4, and 4-picolyl chloride hydrochloride, promoted the reaction smoothly to afford the corresponding α, β-unsaturated λ-lactone derivatives in moderate-to-good yields (46-79%) with high enantioselectivities (up to 88% ee) Natural products (R)-(+)-kavain (70% ee, > 99% ee after single re crystallization) and (S)-(+)-dihydrokavain (84% ee) were also prepared in one step by using this methodology.