57026-80-9

Basic information

• Product Name: 1-(4-METHYLPHENYL)-3-(3-NITROPHENYL)PROP-2-EN-1-ONE
• Synonyms: 1-(4-METHYLPHENYL)-3-(3-NITROPHENYL)-2-PROPEN-1-ONE;1-(4-METHYLPHENYL)-3-(3-NITROPHENYL)PROP-2-EN-1-ONE
• CAS NO: 57026-80-9
• Molecular Formula: C₁₆H₁₃NO₃
• Molecular Weight: 267.28
• Mol File: 57026-80-9.mol
• Article Data: 4

Chemical Properties

• Melting Point: 134 °C
• Boiling Point: 442.5°C at 760 mmHg
• Flash Point: 210.2°C
• Appearance: /
• Density: 1.226g/cm³
• Vapor Pressure: 5E-08mmHg at 25°C
• Refractive Index: 1.639
• CAS DataBase Reference: 1-(4-METHYLPHENYL)-3-(3-NITROPHENYL)PROP-2-EN-1-ONE(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(4-METHYLPHENYL)-3-(3-NITROPHENYL)PROP-2-EN-1-ONE(57026-80-9)
• EPA Substance Registry System: 1-(4-METHYLPHENYL)-3-(3-NITROPHENYL)PROP-2-EN-1-ONE(57026-80-9)

Safety Data

• Hazardous Substances Data: 57026-80-9(Hazardous Substances Data)

Usage

General Description

1-(4-Methylphenyl)-3-(3-nitrophenyl)prop-2-en-1-one is a chemical compound with the molecular formula C16H13NO3. It is a yellow crystalline solid that is commonly used as an intermediate in the synthesis of pharmaceuticals and agrochemicals. 1-(4-METHYLPHENYL)-3-(3-NITROPHENYL)PROP-2-EN-1-ONE contains two aromatic rings, one with a methyl group and the other with a nitro group, attached to a prop-2-en-1-one functional group. It is also known for its potential as an anti-inflammatory and antioxidant agent. 1-(4-Methylphenyl)-3-(3-nitrophenyl)prop-2-en-1-one is an important compound in organic chemistry and has potential applications in the field of medicinal chemistry.

InChI:InChI=1/C16H13NO3/c1-12-5-8-14(9-6-12)16(18)10-7-13-3-2-4-15(11-13)17(19)20/h2-11H,1H3/b10-7+

Upstream product

• 2096-86-8 p-Tolylaceton 
• 99-61-6 3-nitro-benzaldehyde 
• 122-00-9 para-methylacetophenone 

Downstream Products

• 57026-81-0 m-nitrobenzylidene-p-methylacetophenone dibromide 
• 1384736-88-2 (E)-1-(4-((1H-imidazol-1-yl)methyl)phenyl)-3-(3-nitrophenyl)prop-2-en-1-one 
• 1210051-88-9 3-(3-nitrophenyl)-3-(phenylthio)-1-p-tolylpropan-1-one 
• 78743-73-4 [2-Benzoyl-3-(3-nitro-phenyl)-cyclopropyl]-p-tolyl-methanone 
• 84857-21-6 4-(3-Nitro-phenyl)-6-p-tolyl-pyrimidin-2-ylamine 

Relevant articles and documents

An eco-friendly synthesis of 2-pyrazoline derivatives catalysed by CeCl 3· 7 H 2O

Abstract: 1,3,5-triaryl-2-pyrazoline derivatives were synthesised by a condensation reaction between chalcones and phenyl hydrazine using cerium chloride heptahydrate as a catalyst. All these reactions were carried out in ethyl lactate (70%) as a green solvent. Easy and efficient work up, recyclability of solvent and catalyst are the key merits of this protocol. Graphical Abstract:: SYNOPSIS A facile protocol for the synthesis of 1,3,5-triaryl-2-pyrazolines is described. The solvent ethyl lactate, obtained from renewable sources, is biodegradable. The catalyst CeCl 3· 7 H 2O is a water-tolerant Lewis acid with low toxicity. Easy and clean work up, recyclable solvent and catalyst are merits of the protocol. The reaction works well for all systems giving good yields of the desired products.[Figure not available: see fulltext.].

Tudies in Heterocyclic Compounds. Part-XLII. Synthesis and Antibacterial Activity of some New 1,3-Diaryl-2-(arylazo)propan-1,3-diones

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