570368-19-3Relevant academic research and scientific papers
Highly stereoselective anti SN2′ substitutions of (Z)-allylic pentafluorobenzoates with polyfunctionalized zinc-copper reagents
Harrington-Frost, Nicole,Leuser, Helena,Calaza, M. Isabel,Kneisel, Florian F.,Knochel, Paul
, p. 2111 - 2114 (2007/10/03)
(Matrix presented) Allylic substitution reactions of zinc-copper organometallics on (Z)-allylic pentafluorobenzoates proceed with very high regioselectivity and excellent anti selectivity. The high fidelity in transfer of stereochemical information allowed a short synthesis of (+)-ibuprofen (97% ee).
