5704-66-5

Basic information

• Product Name: Pyruvoyl chloride
• Synonyms: Pyruvoyl chloride;Propanoyl chloride, 2-oxo-;2-OXOPROPANOYL CHLORIDE(WXG02573)
• CAS NO: 5704-66-5
• Molecular Formula: C₃H₃ClO₂
• Molecular Weight: 106.50772
• EINECS: -0
• Mol File: 5704-66-5.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 70-80 °C
• Appearance: /
• Density: 1.272±0.06 g/cm3(Predicted)
• CAS DataBase Reference: Pyruvoyl chloride(CAS DataBase Reference)
• NIST Chemistry Reference: Pyruvoyl chloride(5704-66-5)
• EPA Substance Registry System: Pyruvoyl chloride(5704-66-5)

Safety Data

• Hazardous Substances Data: 5704-66-5(Hazardous Substances Data)

Usage

General Description

Pyruvoyl chloride, also known as 2-pyruvoyl chloride, is a chemical compound with the formula C3H3ClO2. It is a reactive and corrosive compound that is used in chemical synthesis and research. Pyruvoyl chloride is commonly used in the production of drugs, pharmaceuticals, and agrochemicals. It is also used as a reagent in organic chemistry reactions, particularly in the creation of heterocyclic compounds. Pyruvoyl chloride is known for its ability to undergo various chemical reactions, such as nucleophilic addition and substitution reactions, making it a versatile and useful compound in the laboratory setting. However, it is important to handle pyruvoyl chloride with caution due to its corrosive and toxic nature.

Upstream product

• 4885-02-3 Dichloromethyl methyl ether 
• 127-17-3 2-oxo-propionic acid 
• 565-62-8 3-methylpent-3-en-2-one 

Downstream Products

• 46114-86-7 pyruvanilide 
• 75131-42-9 2-Oxo-propionic acid N'-[5-(2-chloro-4-trifluoromethyl-phenoxy)-2-nitro-phenyl]-hydrazide 
• 82816-14-6 N-o-tolyl-pyruvamide 
• 86577-47-1 2,6-di-tert-butyl-4-methylphenyl pyruvate 
• 126109-99-7 2-phenyl-1,5-hexadien-3-ol pyruvate ester 
• 126109-93-1 4-phenyl-1,5-hexadien-3-ol pyruvate ester 
• 77920-72-0 N-pyruvoyl-N'-methylphenylalanineamide 
• 139705-00-3 trans-2-hydroxycyclohexyl pyruvate 
• 139704-99-7 3-hydroxy-3-methyl-2-oxo-2,3,4a,5,6,7,8,8a-octahydro-1,4-benzodioxin 
• 72681-70-0 N-(pyruvoyl)-(S)-α-phenylalanine methyl ester 
• 108415-26-5 N-(2-Oxopropionyl)prolin-benzylester 
• 23136-39-2 2-acetyl-5-nitrobenzofuran 
• 1646-26-0 1-(benzo[b]furan-2-yl)ethanone 
• 105897-23-2 methyl 3-(benzyloxy)-5-methoxy-2-(2-oxopropanamido)benzoate 

Relevant articles and documents

Gas-phase reaction of two unsaturated ketones with atomic Cl and O3: Kinetics and products

The rate constants and products for the reactions of atomic Cl and O3 molecule with 3-methyl-3-buten-2-one (MBO332) and 3-methyl-3-penten-2-one (MPO332) were determined in a 100 L Teflon chamber at 293 ± 1 K and atmospheric pressure. For MBO332 and MPO332, the rate constants measured with atomic Cl were (2.38 ± 0.26) × 10-10 and (3.00 ± 0.34) × 10-10 cm3 molecule-1 s-1 using the relative rate method. Using the absolute rate method, the rate constants with O3 measured were (1.18 ± 0.21) × 10-17 and (4.07 ± 0.45) × 10-17 cm3 molecule-1 s-1. The products of these reactions were investigated by the proton-transfer-reaction mass spectrum (PTR-MS). The results indicated that the major products observed in the atomic Cl reaction were formaldehyde together with chloroacetone for MBO332, and acetaldehyde and CH3C(O)C(O)Cl for MPO332. For O3 reactions, butanedione and formaldehyde were the main products of MBO332, while butanedione and acetaldehyde were the main products of MPO332. Possible reaction mechanisms were proposed and discussed and the atmospheric implications of these reactions were also discussed.

Acid chlorides from α-keto acids with α,α-dichloromethyl methyl ether: Pyruvoyl chloride

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