5705-61-3Relevant academic research and scientific papers
A Simple Synthesis of Natural Products with 5-H-Furan-2-on Structure
Reisch, Johannes,Mester, Zita
, p. 635 - 638 (1983)
Starting from an aldehyde, γ-Yliden-α,β-butenolides were synthesised simply by the use of 2,5-dihydro-2,5-dimethoxyfuran in the presence of trimethylchlorosilane. - Keywords: 2,5-Dihydro-2,5-dimethoxyfuran, γ-Yliden-α,β-butenolide
A new, highly stereoselective synthesis of β-unsubstituted (Z)-γ-alkylidene-butenolides using bromine as a removable stereocontrol element
Boukouvalas, John,Beltrán, Paola P.,Lachance, Nicolas,C?té, Sébastien,Maltais, Fran?ois,Pouliot, Martin
, p. 219 - 222 (2007/10/03)
Several β-unsubstituted (Z)-γ-alkylidenebutenolides have been prepared in highly stereocontrolled fashion by implementing a steric directing group stratagem in the vinylogous aldol condensation of butenolides with aldehydes. Applications to the synthesis of the antitumor heptene (S)-melodorinol and a thiophenelactone from Chamaemelum nobile L. are described. Georg Thieme Verlag Stuttgart.
A NEW SYNTHESIS OF 5-METHYLENE-2(5H)-FURANONE DERIVATIVES
Antonioletti, Roberto,D'Auria, Maurizio,Mico, Antonella De,Piancatelli, Giovanni,Scettri, Arrigo
, p. 3805 - 3808 (2007/10/02)
5-methylene-2(5H)-furanone derivatives are easily obtained by treatment of tertiary 2-furylcarbinols with pyridinium dichromate in dimethylformamide solution.Through this procedure, a natural product, the thiophene lactone, isolated from Chamaemelum Nobile L., has been synthesized.
SYNTHESIS OF 4-YLIDENEBUTENOLIDES FROM 2-TRIMETHYLSILOXYFURAN
Asaoka, Morio,Yanagida, Noboru,Ishibashi, Keiji,Takei, Hisashi
, p. 4269 - 4270 (2007/10/02)
Dehydration or dealkoxylation of the reaction products of various aldehydes, ketones, and acetals with 2-trimethylsiloxyfuran gave corresponding 4-ylidenebutenolides in good to high overall yields.
