57052-87-6Relevant academic research and scientific papers
Design, synthesis, and evaluation of conformationally constrained tongs, new inhibitors of HIV-1 protease dimerization
Bouras, Ahmed,Boggetto, Nicole,Benatalah, Zohra,De Rosny, Eve,Sicsic, Sames,Reboud-Ravaux, Michèle
, p. 957 - 962 (2007/10/03)
The active form of human immunodeficiency virus type 1 protease (HIV-1 PR) is a homodimeric structure in which two subunits are linked through a two-stranded antiparallel β-sheet consisting of the N- and C-termini of each monomer. To inhibit the dimerizat
