5706-22-9Relevant academic research and scientific papers
Catalytic Sulfur-Enabled Dehydrobicyclization of 1,6-Enynes toward Arylated Indeno[1,2-c]thiophenes
Wu, Ya-Nan,Fu, Rong,Wang, Nan-Nan,Hao, Wen-Juan,Li, Guigen,Tu, Shu-Jiang,Jiang, Bo
, p. 4762 - 4770 (2016/07/06)
A new copper-catalyzed sulfur-enabled dehydrobicyclization of 1,6-enynes using potassium sulfide as a sulfurating reagent has been established, providing a straightforward access toward arylated indeno[1,2-c]thiophenes with moderate to good yields. This sulfur incorporation pathway involves Michael addition, 5-exo-dig/5-endo-trig bicyclization and dehydrogenation sequence, resulting in continuous multiple bond-forming events including C-S and C-C bonds to rapidly construct functional organic molecules.
