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2-Methoxy-benzamidine hydrochloride, with the molecular formula C8H11ClN2O and a molecular weight of 190.64 g/mol, is a white to off-white crystalline powder. It is a chemical compound that serves as a reagent in organic synthesis and an intermediate in the pharmaceutical industry. Known for its ability to inhibit serine proteases, it is a valuable tool in biochemical and pharmaceutical research and is used as a precursor in the synthesis of various pharmaceutical and agrochemical compounds.

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  • 57075-83-9 Structure
  • Basic information

    1. Product Name: 2-METHOXY-BENZAMIDINE HCL
    2. Synonyms: AMINO(2-METHOXYPHENYL)METHANIMINIUM CHLORIDE;2-Methoxybenzimidamide hydrochloride;2-Methoxy-Benzamidine Hydrochloride(WX690199)
    3. CAS NO:57075-83-9
    4. Molecular Formula: C8H10N2O*ClH
    5. Molecular Weight: 0
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 57075-83-9.mol
  • Chemical Properties

    1. Melting Point: 157-158 °C(Solv: ethanol (64-17-5); ethyl ether (60-29-7))
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: /
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: Sealed in dry,Room Temperature
    8. Solubility: N/A
    9. CAS DataBase Reference: 2-METHOXY-BENZAMIDINE HCL(CAS DataBase Reference)
    10. NIST Chemistry Reference: 2-METHOXY-BENZAMIDINE HCL(57075-83-9)
    11. EPA Substance Registry System: 2-METHOXY-BENZAMIDINE HCL(57075-83-9)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 57075-83-9(Hazardous Substances Data)

57075-83-9 Usage

Uses

Used in Organic Synthesis:
2-Methoxy-benzamidine hydrochloride is used as a reagent in organic synthesis for its ability to facilitate the formation of desired chemical products through various reactions.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, 2-Methoxy-benzamidine hydrochloride is used as an intermediate, playing a crucial role in the development and production of various drugs.
Used in Biochemical Research:
2-Methoxy-benzamidine hydrochloride is used as a research tool in biochemical studies due to its ability to inhibit the activity of serine proteases, which helps in understanding the functions and mechanisms of these enzymes.
Used in Pharmaceutical and Agrochemical Compounds Synthesis:
As a precursor, 2-Methoxy-benzamidine hydrochloride is used in the synthesis of a wide range of pharmaceutical and agrochemical compounds, contributing to the development of new and improved products in these fields.

Check Digit Verification of cas no

The CAS Registry Mumber 57075-83-9 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,7,0,7 and 5 respectively; the second part has 2 digits, 8 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 57075-83:
(7*5)+(6*7)+(5*0)+(4*7)+(3*5)+(2*8)+(1*3)=139
139 % 10 = 9
So 57075-83-9 is a valid CAS Registry Number.

57075-83-9SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 17, 2017

Revision Date: Aug 17, 2017

1.Identification

1.1 GHS Product identifier

Product name 2-Methoxybenzenecarboximidamide hydrochloride (1:1)

1.2 Other means of identification

Product number -
Other names 2-Methoxybenzimidamide hydrochloride

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:57075-83-9 SDS

57075-83-9Upstream product

57075-83-9Relevant articles and documents

Macrocyclic MCL-1 inhibitors and methods of use

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Paragraph 0534, (2019/02/28)

The present disclosure provides for compounds of Formula (I) wherein A2, A3, A4, A6, A7, A8, A15, RA, R5, R9, R10A, R10B, R11, R12, R13, R14, R16, W, X, and Y have any of the values defined in the specification, and pharmaceutically acceptable salts thereof, that are useful as agents for the treatment of diseases and conditions, including cancer. Also provided are pharmaceutical compositions comprising compounds of Formula (I).

MACROCYCLIC MCL-1 INHIBITORS AND METHODS OF USE

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Paragraph 00299, (2019/03/05)

The present disclosure provides for compounds of formula (I), wherein A2, A3, A4, A6, A7, A8, A15, RA, R5, R9, R10A, R10B, R11, R12, R13, R14, R16, W, X, and Y have any of the values defined in the specification, and pharmaceutically acceptable salts thereof, that are useful as agents in the treatment of diseases and conditions, including cancer. Also provided are pharmaceutical compositions comprising compounds of formula (I).

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