571-39-1

Usage

Uses

Used in Pharmaceutical Industry:
1-ANDROSTENEDIONE is used as an anabolic agent for promoting muscle growth and strength. It is particularly useful for athletes and bodybuilders who seek to enhance their physical performance and improve their overall body composition.
Used in Research and Development:
1-ANDROSTENEDIONE serves as a valuable compound in the field of research and development, particularly in the study of anabolic androgen steroids and their effects on the human body. It can be used to develop new drugs and therapies for various medical conditions.
Used in Anti-doping Efforts:
1-ANDROSTENEDIONE is used as a marker in anti-doping tests to detect the use of banned substances in sports. Its presence in an athlete's urine can indicate the use of anabolic androgen steroids, which are prohibited in competitive sports.
Used in Forensic Analysis:
In forensic analysis, 1-ANDROSTENEDIONE can be used to identify the presence of anabolic androgen steroids in biological samples, such as blood or urine. This information can be crucial in cases involving the use of performance-enhancing drugs or the investigation of drug-related crimes.
Used in Sports Medicine:
1-ANDROSTENEDIONE is used as a diagnostic tool in sports medicine to assess the effects of anabolic androgen steroids on athletes' bodies. It can help medical professionals understand the potential risks and benefits associated with the use of these substances in sports.

Upstream product

• 846-46-8 (5ξ)-androstane-3,17-dione 
• 897-06-3 Androsta-1,4-diene-3,17-dione 
• 1229-12-5 androstane-3,17-dione 
• 846-46-8 (5ξ)-androstane-3,17-dione 

Relevant academic research and scientific papers

Steroidal isomers with uniform mass spectra of their per-TMS derivatives: Synthesis of 17-hydroxyandrostan-3-ones, androst-1-, and -4-ene-3,17-diols

In human sports doping control analysis most of the steroids are analyzed after enzymatic hydrolysis of the glucuronides as per-trimethylsilyl (TMS) derivatives applying gas chromatography-mass spectrometry (GC-MS). According to the recommendations of the World Anti-Doping Agency the identification of analytes should be based on retention time and on mass spectrometric characterization. This study shows that the bis-TMS derivatives of 16 specific C19 steroids, namely the stereoisomers of 5ξ-androst-1-ene-3ξ,17ξ-diol (8 isomers), androst-4-ene-3ξ,17ξ-diol (4 isomers), and 17ξ-hydroxy-5ξ-androstan-3-one (4 isomers), reveal very similar mass spectra. As a rule, when taking the retention times, which are provided as Kovac indices for all these isomers, into account, a restriction to two or three possible isomers is possible. Reliable identification should additionally include a comparison of the retention times of the analytes with the reference compounds measured concomitantly. In some cases standard addition may be appropriate. Due to the limited availability, the above mentioned isomers were synthesized by reduction of the corresponding α,β-unsaturated oxo steroids either with K-Selectride or by catalytic hydrogenation (Pd/C as catalyst). The products of the reactions were identified by means of nuclear magnetic resonance (NMR) characterization and by further reduction to the corresponding 5ξ-androstane-3ξ,17ξ-diols and GC-MS comparison with commercially available reference standards.

HIO3 and I2O5: Mild and selective alternative reagents to IBX for the dehydrogenation of aldehydes and ketones

Economic and convenient: Iodic acid (1) and iodine pentoxide (2) form complexes 3 and 4, respectively, with DMSO when heated at 80°C for 1 h. The complexes are efficient agents for the dehydrogenation of ketones and aldehydes at 45-65°C. X-ray crystallographic analysis (see picture) shows that the iodine pentoxide. DMSO complex 4 self-assembles into a remarkable helix in the solid state.

Modulation of the reactivity profile of IBX by ligand complexation: Ambient temperature dehydrogenation of aldehydes and ketones to α,β-unsaturated carbonyl compounds

The reactivity profile of IBX can be altered by complexation with various ligands (e. g. 1-4). A new complex, IBX·MPO, is a remarkably effective oxidant and allows the room-temperature dehydrogenation of carbonyl compounds, for example, the formation of cyclooctenones 6 and 7 from cyclooctanone 5. IBX = iodoxybenzoic acid; MPO = 4-methoxypyridine-N-oxide.

Unusual Enolizations in 19-Nor-3-ketosteroids

The direction of enolization of 19-nor-3-ketosteroids was found to proceed predominantly towards C-2 irrespective of the ring junction at C-5.