57100-18-2 Usage
Description
Pseudoisocytidine (Ψ), also known as Ψ, is a modified nucleoside that is integral to the structure of tRNA and rRNA. It is formed through the isomerization of cytidine catalyzed by a specific enzyme and is instrumental in stabilizing the three-dimensional conformation of these RNA molecules. Pseudoisocytidine plays a pivotal role in the decoding process during protein synthesis, enhancing the efficiency and accuracy of tRNA and rRNA function by facilitating the correct pairing of codons and anticodons. Furthermore, it has emerged as a potential target for the development of new antibacterial drugs, given its essential role in the survival of certain pathogenic bacteria. Pseudoisocytidine is a vital element of the genetic code, with significant implications for both fundamental biological processes and the potential for therapeutic applications.
Uses
Used in Pharmaceutical Development:
Pseudoisocytidine is utilized as a target for the development of novel antibacterial agents, specifically for the creation of drugs that can inhibit the survival of certain pathogenic bacteria. Its essential role in bacterial RNA makes it a promising candidate for the design of new antibiotics that could combat resistant strains.
Used in Basic Biological Research:
In the field of molecular biology, Pseudoisocytidine is employed as a subject of study to understand its role in the stabilization of tRNA and rRNA structures. This research is crucial for gaining insights into the decoding process during protein synthesis and the overall regulation of gene expression.
Used in Biochemistry Education:
Pseudoisocytidine serves as a teaching tool in biochemistry and molecular biology curricula, helping students to comprehend the complex interactions within the genetic code and the mechanisms of protein synthesis. Understanding the function of Pseudoisocytidine can provide a deeper appreciation of the nuances of RNA structure and function.
Used in Drug Resistance Research:
In the context of antibiotic resistance, Pseudoisocytidine is explored as a potential target to develop new strategies to overcome resistance in bacteria. By focusing on this essential component of bacterial RNA, researchers aim to create drugs that can effectively target and neutralize resistant pathogens.
Used in Diagnostics:
Pseudoisocytidine could be employed in the development of diagnostic tools that detect the presence or activity of this modified nucleoside in clinical samples. Such diagnostics could aid in the identification of specific bacterial infections and guide appropriate treatment strategies.
Check Digit Verification of cas no
The CAS Registry Mumber 57100-18-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,7,1,0 and 0 respectively; the second part has 2 digits, 1 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 57100-18:
(7*5)+(6*7)+(5*1)+(4*0)+(3*0)+(2*1)+(1*8)=92
92 % 10 = 2
So 57100-18-2 is a valid CAS Registry Number.
InChI:InChI=1/C9H13N3O5/c10-9-11-1-3(8(16)12-9)7-6(15)5(14)4(2-13)17-7/h1,4-7,13-15H,2H2,(H3,10,11,12,16)/t4-,5-,6-,7+/m1/s1
57100-18-2Relevant articles and documents
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Hirota,K. et al.
, p. 1193 - 1197 (1978)
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2,4-Dichloro-5-(β-D-ribofuranosyl) pyrimidines and substituted derivatives
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, (2008/06/13)
A C-nucleoside compound, 2,4-dichloro-5-(2,3,5-Tri-O-acetyl-β-D-Ribofuranosyl)pyrimidine, useful as a primary starting material in the synthesis of various C-nucleoside compounds having antitumor, antiviral and/or antibacterial activity. A structural formula is as follows: STR1 The location of the 2,4-dichloro members on the heterocycle, with the active sites of the carbohydrate being blocked, provides an intermediate compound well adapted for a variety of nucleophilic substitutions. Such procedures have yielded several novel analogs of known pyrimidine nucleosides found in RNA, as well as other compounds which have demonstrated chemotherapeutic utility.
