57102-09-7

Basic information

• Product Name: 1,25-dihydroxy-previtamin D(3)
• Synonyms: 1,25-dihydroxy-previtamin D(3)
• CAS NO: 57102-09-7
• Molecular Formula: C₂₇H₄₄O₃
• Molecular Weight: 416.63646
• Mol File: 57102-09-7.mol
• Article Data: 6

Chemical Properties

• Boiling Point: 564.5°Cat760mmHg
• Flash Point: 238.2°C
• Appearance: /
• Density: 1.119g/cm³
• Vapor Pressure: 4.28E-15mmHg at 25°C
• Refractive Index: 1.605
• Storage Temp.: Amber Vial, -86°C Freezer, Under inert atmosphere
• Solubility: Chloroform (Slightly), Methanol (Slightly)
• Stability: Light Sensitive, Temperature Sensitive
• CAS DataBase Reference: 1,25-dihydroxy-previtamin D(3)(CAS DataBase Reference)
• NIST Chemistry Reference: 1,25-dihydroxy-previtamin D(3)(57102-09-7)
• EPA Substance Registry System: 1,25-dihydroxy-previtamin D(3)(57102-09-7)

Safety Data

• Hazardous Substances Data: 57102-09-7(Hazardous Substances Data)

Usage

Uses

1α,25-Dihydroxyprevitamin D3 is used to stimulate expression and translocation of protein kinase Calpha and Cdelta via. It is related to Vitamin D (V676045)

InChI:InChI=1/C27H44O3/c1-18(8-6-14-26(3,4)30)23-12-13-24-20(9-7-15-27(23,24)5)10-11-21-16-22(28)17-25(29)19(21)2/h9-11,18,22-25,28-30H,6-8,12-17H2,1-5H3/b11-10-/t18-,22+,23-,24+,25-,27-/m1/s1

Upstream product

• 134458-47-2 1α-<((tert-butyldiphenyl)silyl)oxy>-6,7-dehydro-25-hydroxyprevitamin D3 (tert-butyldiphenyl)silyl ether 
• 134458-42-7 (3S,5R)-3,5-bis<((tert-butyldiphenyl)silyl)oxy>-1-(2,2-dibromoethenyl)-2-2-methylcyclohex-1-ene 
• 134458-40-5 (3S,5R)-3,5-bis<((tert-butyldiphenyl)silyl)oxy>-1-formyl-2-methylcyclohex-1-ene 
• 134485-15-7 (3S,5R)-3,5-bis<((tert-butyldiphenyl)silyl)oxy>-1-ethenyl-2-methylcyclohex-1-ene 
• 134458-38-1 (3S,5R)-3,5-bis<((tert-butyldiphenyl)silyl)oxy>-1-ethynyl-2-methylcyclohex-1-ene 
• 134458-36-9 25-hydroxy-de-A,B-cholest-8-en-8-yl trifluoromethanesulfonate 
• 115540-14-2 (1S,2R,4S,6S)-2,4-diacetoxy-2-ethynyl-1-methyl-7-oxabicyclo<4.1.0>heptane 
• 113375-51-2 (3S,5R)-1-ethynyl-3,5-dihydroxy-2-methylcyclohex-1-ene 
• 113490-28-1 de-A,B-25-cholesta-8,25-dien-8-yl trifluromethanesulfonate 
• 86323-06-0 (3bR,5aR,6R,8aR,10S)-10-[(R)-5-(tert-Butyl-dimethyl-silanyloxy)-2-methyl-3-oxo-cyclohex-1-enyl]-6-((R)-5-hydroxy-1,5-dimethyl-hexyl)-5a-methyl-2-phenyl-4,5,5a,6,7,8,8a,10-octahydro-3bH-2,3a,10a-triaza-dicyclopenta[a,f]naphthalene-1,3-dione 
• 86307-42-8 (3bR,5aR,6R,8aR,10S)-10-[(S)-5-(tert-Butyl-dimethyl-silanyloxy)-2-methyl-cyclohex-1-enyl]-6-((R)-5-hydroxy-1,5-dimethyl-hexyl)-5a-methyl-2-phenyl-4,5,5a,6,7,8,8a,10-octahydro-3bH-2,3a,10a-triaza-dicyclopenta[a,f]naphthalene-1,3-dione 
• 86307-43-9 (3bR,5aR,6R,8aR,10S)-6-((R)-5-Hydroxy-1,5-dimethyl-hexyl)-10-((R)-5-hydroxy-2-methyl-3-oxo-cyclohex-1-enyl)-5a-methyl-2-phenyl-4,5,5a,6,7,8,8a,10-octahydro-3bH-2,3a,10a-triaza-dicyclopenta[a,f]naphthalene-1,3-dione 
• 86307-41-7 (3bR,5aR,6R,8aR,10S)-6-((R)-5-Hydroxy-1,5-dimethyl-hexyl)-10-((S)-5-hydroxy-2-methyl-cyclohex-1-enyl)-5a-methyl-2-phenyl-4,5,5a,6,7,8,8a,10-octahydro-3bH-2,3a,10a-triaza-dicyclopenta[a,f]naphthalene-1,3-dione 
• 23357-18-8 25-hydroxy previtamin D₃ 

Downstream Products

• 61954-91-4 1α,3β,25-trihydroxycholesta-5,7-diene 
• 96862-25-8 1a,25-Dihydroxytachysterol₃ 
• 32222-06-3 calcitriol 

Relevant articles and documents

Synthesis, biological activity, and conformational analysis of CD-ring modified trans-decalin 1α,25-dihydroxyvitamin D analogs

A novel series of analogs of 1.25-dihydroxyvitamin D3, the hormonally active metabolite of vitamin D3, characterised by the presence of a trans-fused decalin CD-ring system, possesses surprising biological activities in combination w

14-Epi stereoisomers of 25-hydroxy- and 1α,25-dihydroxyvitamin D3: Synthesis, isomerization to previtamins, and biological studies

The C-14 epimers of vitamin D, 14-epi-25-hydroxyvitamin D3 (4) and 14- epi-1α,25-dihydroxyvitamin D3 (5), were synthesized, and their isomerization via [1,7]-sigmatropic hydrogen shifts to the corresponding previtamin forms (4' and 5

1α,25-dihydroxyprevitamin D3: Synthesis of the 9,14,19,19,19,-pentadeuterio derivative and a kinetic study of its [1,7]-sigmatropic shift to 1α,25-dihytdroxyvitamin D31

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