57114-97-3Relevant academic research and scientific papers
TOLL-LIKE RECEPTOR SIGNALING INHIBITORS
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Paragraph 00286, (2019/07/20)
Di- and triaryl-substituted heteroaromatic compounds have Toll-like receptor inhibitory activity, including at TLR2, TLR4, TLR7, and/or TLR9. Compounds and compositions have applications in the treatment of diseases and conditions mediated by Toll-like receptors and related receptors, such as bacterial sepsis, autoimmune disease, lupus erythematosus, ischemia-reperfusion injury, stroke, metabolic disease, obesity-related metabolic inflammation, gout, and cancer.
An efficient oxidation of 2-pyrazolines and isoxazolines by bis-bromine-1,4-diazabicyclo[2.2.2]octane complex (DABCO-Br2)
Azarifar, Davood,Khosravi, Kaveh,Veisi, Rahman-Ali
experimental part, p. 178 - 184 (2010/10/03)
An efficient and simple procedure has been developed for the oxidation of 1,3,5-trisubstituted 4,5-dihydro-1H-pyrazoles and -isoxazoles to their corresponding aromatic derivatives promoted by bis-bromine-1,4-diazabicyclo[2.2. 2]octane complex (DABCO-Brsu
Oxidative aromatization of 3,5-disubstituted isoxazolines to the corresponding isoxazoles with itN,N,N′,N′-tetrabromobenzene-1,3-disolphonamide (TBBDS) and 1,3-dibromo-5,5-dimethylhydantoin (DBH) as efficient reagents under mild reaction conditions
Azarifar, Davood,Maleki, Behrooz,Mohammadi, Kobra
, p. 683 - 689 (2008/03/12)
The oxidation of 3,5-disubstituted isoxazolines to the corresponding isoxazoles has been carried out using N,N,N′,N′-tetrabromobenzene-1,3-disolphonamide and 1,3-dibromo-5,5-dimethylhydantoin (DBH) as effective oxidizing agents under mild conditions at rt
