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571189-23-6

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571189-23-6 Usage

General Description

1-BOC-4-(2-AMINO-4-PYRIDINYL)-PIPERAZINE is a chemical compound that belongs to the class of piperazine derivatives. It is a white to off-white powder with a molecular formula of C16H24N4O2 and a molecular weight of 300.38 g/mol. 1-BOC-4-(2-AMINO-4-PYRIDINYL)-PIPERAZINE is commonly used in medicinal chemistry and pharmaceutical research as a building block for the synthesis of various bioactive compounds and pharmaceutical drugs. It has been studied for its potential therapeutic properties, including its activity as an antagonist at certain receptor sites in the central nervous system. Additionally, 1-BOC-4-(2-AMINO-4-PYRIDINYL)-PIPERAZINE is also used as a chemical intermediate in the production of other advanced materials and agrochemicals.

Check Digit Verification of cas no

The CAS Registry Mumber 571189-23-6 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 5,7,1,1,8 and 9 respectively; the second part has 2 digits, 2 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 571189-23:
(8*5)+(7*7)+(6*1)+(5*1)+(4*8)+(3*9)+(2*2)+(1*3)=166
166 % 10 = 6
So 571189-23-6 is a valid CAS Registry Number.

571189-23-6SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 17, 2017

Revision Date: Aug 17, 2017

1.Identification

1.1 GHS Product identifier

Product name tert-butyl 4-(2-aminopyridin-4-yl)piperazine-1-carboxylate

1.2 Other means of identification

Product number -
Other names -

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

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Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:571189-23-6 SDS

571189-23-6Downstream Products

571189-23-6Relevant articles and documents

PYRIDINYL HETEROCYCLYL COMPOUNDS FOR THE TREATMENT OF AUTOIMMUNE DISEASE

-

Page/Page column 39-40, (2020/01/08)

The present invention relates to compounds of formula (I), a b (I), wherein R1 to R4 and L are as described herein, and their pharmaceutically acceptable salt, enantiomer or diastereomer thereof, and compositions including the compounds and methods of using the compounds.

Discovery of piperazinylimidazo[1,2-a]pyridines as novel S4 binding elements for orally active Factor Xa inhibitors

Imaeda, Yasuhiro,Kawamoto, Tetsuji,Tobisu, Mamoru,Konishi, Noriko,Hiroe, Katsuhiko,Kawamura, Masaki,Tanaka, Toshimasa,Kubo, Keiji

, p. 3125 - 3140 (2008/09/19)

We have recently reported the discovery of orally active sulfonylalkylamide Factor Xa (FXa) inhibitors, as typified by compound 1 (FXa IC50 = 0.061 μM). Since the pyridylpiperidine moiety was not investigated in our previous study, we conducted detailed structure-activity relationship studies on this S4 binding element. This investigation led to the discovery of piperazinylimidazo[1,2-a]pyridine 2b as a novel and potent FXa inhibitor (FXa IC50 = 0.021 μM). Further modification resulted in the discovery of 2-hydroxymethylimidazo[1,2-a]pyridine 2e (FXa IC50 = 0.0090 μM), which was found to be a selective and orally bioavailable FXa inhibitor with reduced CYP3A4 inhibition.

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