57132-22-6Relevant articles and documents
Enantioselective Bromolactonization of Trisubstituted Olefinic Acids Catalyzed by Chiral Pyridyl Phosphoramides
Nishikawa, Yasuhiro,Hamamoto, Yuhta,Satoh, Rika,Akada, Naho,Kajita, Shuhei,Nomoto, Marina,Miyata, Megumi,Nakamura, Madoka,Matsubara, Chinatsu,Hara, Osamu
, p. 18880 - 18885 (2018/12/04)
Enantioselective bromolactonization of trisubstituted olefinic acids producing synthetically useful chiral lactones with two contiguous asymmetric centers has remained mainly unexplored except for the 6-exo cyclization mode. In this work, the 5-exo- and 6
Regioselective aerobic oxidative Heck reactions with electronically unbiased alkenes: Efficient access to α-alkyl vinylarenes
Zheng, Changwu,Stahl, Shannon S.
supporting information, p. 12771 - 12774 (2015/08/18)
Branched-selective oxidative Heck coupling reactions have been developed between arylboronic acids and electronically unbiased terminal alkenes. The reactions exhibit high catalyst-controlled regioselectivity favoring the less common branched isomer. The reactions employ a catalyst composed of Pd(TFA)2/dmphen (TFA = trifluoroacetate, dmphen = 2,9-dimethyl-1,10-phenanthroline) and proceed efficiently at 45-60 °C under 1 atm of O2 without requiring other additives. A broad array of functional groups, including aryl halide, allyl silane and carboxylic acids are tolerated.
Nonenzymatic kinetic resolution of α-aryl substituted allylic alcohols catalyzed by acyl transfer catalyst Np-PIQ
Jiang, Shan-Shan,Gu, Bo-Qi,Zhu, Ming-Yu,Yu, Xingxin,Deng, Wei-Ping
, p. 1187 - 1191 (2015/02/19)
Chiral α-aryl substituted allylic alcohols are important versatile synthetic intermediates. We report here an effective nonenzymatic kinetic resolution of racemic α-aryl substituted allylic alcohols by introducing different aryl groups with acyl transfer
C2-symmetric cyclic selenium-catalyzed enantioselective bromoaminocyclization
Chen, Feng,Tan, Chong Kiat,Yeung, Ying-Yeung
supporting information, p. 1232 - 1235 (2013/03/28)
A catalytic asymmetric bromocyclization of trisubstituted olefinic amides that uses a C2-symmetric mannitol-derived cyclic selenium catalyst and a stoichiometric amount of N-bromophthalimide is reported. The resulting enantioenriched pyrrolidine products, which contain two stereogenic centers, can undergo rearrangement to yield 2,3-disubstituted piperidines with excellent diastereoselectivity and enantiospecificity.