57160-45-9Relevant academic research and scientific papers
Diastereoface Discrimination in the Addition of Acetylide to a Chiral Aldehyde, Leading to a Synthesis of (+)-Deoxybiotin in Enantiomerically Pure Form Starting from L-Cysteine
Fujisawa, Tamotsu,Nagai, Michiharu,Koike, Yoshihiro,Shimizu, Makoto
, p. 5865 - 5867 (2007/10/02)
Complete diastereofacial discrimination was observed upon addition of the chlorozinc acetylide derived from 1-hexyne to a chiral aldehyde prepared from L-cysteine.The addition product was used in a short synthesis of (+)-deoxybiotin, a precursor of (+)-bi
