57165-01-2 Usage
Uses
Used in Pharmaceutical Industry:
N-(4-amino-2-methylphenyl)methanesulfonamide(SALTDATA: FREE) is used as a potential antineoplastic agent for its ability to inhibit tumor growth. It is being studied for its potential use in cancer treatment, where it may offer therapeutic benefits in managing various types of cancer.
Used in Research and Development:
In the field of research and development, N-(4-amino-2-methylphenyl)methanesulfonamide(SALTDATA: FREE) serves as a subject of investigation for its potential medicinal properties. Scientists and researchers explore its mechanisms of action, efficacy, and safety profile to further understand its role in cancer treatment and other possible applications in medicine.
Check Digit Verification of cas no
The CAS Registry Mumber 57165-01-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,7,1,6 and 5 respectively; the second part has 2 digits, 0 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 57165-01:
(7*5)+(6*7)+(5*1)+(4*6)+(3*5)+(2*0)+(1*1)=122
122 % 10 = 2
So 57165-01-2 is a valid CAS Registry Number.
InChI:InChI=1/C8H12N2O2S/c1-6-5-7(9)3-4-8(6)10-13(2,11)12/h3-5,10H,9H2,1-2H3
57165-01-2Relevant academic research and scientific papers
Lead optimization of selective tubulin inhibitors as anti-trypanosomal agents
Zhao, Anran,Li, Yaxin,Orahoske, Cody M.,Schnur, Brittny,Sabbagh, Abboud,Zhang, Wenjing,Li, Bibo,Su, Bin
, p. 1517 - 1528 (2019/03/05)
Previously synthesized tubulin inhibitors showed promising in vitro selectivity and activity against Human African Trypanosomiasis. Current aim is to improve the ligand efficiency and reduce overall hydrophobicity of the compounds, by lead optimization. V
QUINONE-IMIDES : REGIOSPECIFICITY OF NUCLEOPHILIC ATTACK ON N-ALKANESULPHONYL-N'-ALKANOYL 1,4-BENZOQUINONE-IMINES.
Rajappa, Srinivasaschari,Shenoy, Sharada J.
, p. 5739 - 5746 (2007/10/02)
Substrates such as (2) undergo regiospecific attack by azide and thiocyanate ions at the terminus of the C=C-C=N-CO system.In the case of addition of azide, this is proved by the detailed analysis of the 1H and 13C NMR spectra of the products (11) derived from the quinone-imides (8).The structure of the products obtained by the addition of thiocyanate to the quinone-imides (10) and (20) is proved by their facile cyclisation to the 2-aminobenzothiazoles (18) and (21) respectively.
