57183-85-4Relevant academic research and scientific papers
Metal-Free meta-Selective Alkyne Oxyarylation with Pyridine N-Oxides: Rapid Assembly of Metyrapone Analogues
Chen, Xiangyu,Ruider, Stefan A.,Hartmann, Rolf W.,González, Leticia,Maulide, Nuno
, (2016)
An efficient metal-free oxyarylation of electron-poor alkynes with pyridine N-oxides has been developed. This transformation affords meta-substituted pyridines analogous to the drug metyrapone in high regioselectivities. Density functional theory (DFT) ca
