5719-46-0 Usage
Uses
Used in Pharmaceutical Industry:
4-chloro-5,7-dihydro-2-methylthieno[3,4-d]pyrimidine is used as a key intermediate in the synthesis of various bioactive compounds. Its heterocyclic nature and functional groups make it a valuable component in the development of new drugs with potential therapeutic applications.
Used in Agrochemical Industry:
In the agrochemical sector, 4-chloro-5,7-dihydro-2-methylthieno[3,4-d]pyrimidine serves as a crucial building block for the creation of novel agrochemicals. Its unique structure and functional groups contribute to the development of effective pesticides and other agricultural chemicals.
Used in Medicinal Chemistry Research:
4-chloro-5,7-dihydro-2-methylthieno[3,4-d]pyrimidine is utilized as a significant target in medicinal chemistry research. Its demonstrated biological activities, such as antimicrobial and antiviral properties, make it a promising candidate for the discovery and development of new therapeutic agents.
Check Digit Verification of cas no
The CAS Registry Mumber 5719-46-0 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 5,7,1 and 9 respectively; the second part has 2 digits, 4 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 5719-46:
(6*5)+(5*7)+(4*1)+(3*9)+(2*4)+(1*6)=110
110 % 10 = 0
So 5719-46-0 is a valid CAS Registry Number.
InChI:InChI=1/C7H7ClN2S/c1-4-9-6-3-11-2-5(6)7(8)10-4/h2-3H2,1H3
5719-46-0Relevant academic research and scientific papers
Pyrimidine ortho-quinodimethanes
Tome, Augusto C.,Cavaleiro, Jose A.S.,Storr, Richard C.
, p. 1735 - 1746 (2007/10/03)
The pyrimidine sulfones 10, R = Me; Nu = OMe, NEt2, SPh, H and 11, R = Ph; Nu = OMe were synthesised from the dihydrothienopyrimidones 7, R = Me, Ph by conversion to the chloro derivatives 8 followed by oxidation with mCPBA and reaction with the appropriate nucleophile or hydrogen and Pd. Heating of the sulfones in 1,2,4-trichlorobenzene gave the pyrimidine o-quinodimethanes which were intercepted in Diels-Alder reactions to give tetrahydroquinazolines.
Pyrimidine o-quinodimethanes: Formation of 1:1 and 2:1 adducts with dienophiles
Tome,Cavaleiro,Storr
, p. 6639 - 6642 (2007/10/02)
Pyrimidine fused dihydrothiophene S,S-dioxides 7 undergo thermal elimination of sulfur dioxide to give the pyrimidine o-quinodimethanes 8 which can be intercepted in Diels-Alder reactions to give substituted 5,6,7,8-tetrahydroquinazolines; these form cyclooctapyrimidines on heating with more dienophile.
