57197-03-2

Basic information

• Product Name: 7-Methyl-3-methylene-1-octanol
• Synonyms: 7-Methyl-3-methylene-1-octanol;Bupleurol
• CAS NO: 57197-03-2
• Molecular Formula: C10H20O
• Molecular Weight: 156.27
• Mol File: 57197-03-2.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 7-Methyl-3-methylene-1-octanol(CAS DataBase Reference)
• NIST Chemistry Reference: 7-Methyl-3-methylene-1-octanol(57197-03-2)
• EPA Substance Registry System: 7-Methyl-3-methylene-1-octanol(57197-03-2)

Safety Data

• Hazardous Substances Data: 57197-03-2(Hazardous Substances Data)

Upstream product

• 102880-60-4 (±)-3,7-dimethyloctane-1,3-diol 
• 106-25-2 Nerol 
• 106-21-8 tetrahydrogeraniol 
• 57196-99-3 6-isopropyl-3a-methyl-hexahydro-borolo[1,2-b][1,2]oxaborole 

Relevant articles and documents

General, Auxiliary-Enabled Photoinduced Pd-Catalyzed Remote Desaturation of Aliphatic Alcohols

A general, efficient, and site-selective visible light-induced Pd-catalyzed remote desaturation of aliphatic alcohols into valuable allylic, homoallylic, and bis-homoallylic alcohols has been developed. This transformation operates via a hybrid Pd-radical mechanism, which synergistically combines the favorable features of radical approaches, such as a facile remote C-H HAT step, with that of transition-metal-catalyzed chemistry (selective β-hydrogen elimination step). This allows achieving superior degrees of regioselectivity and yields in the desaturation of alcohols compared to those obtained by the state-of-the-art desaturation methods. The HAT at unactivated C(sp3)-H sites is enabled by the easily installable/removable Si-auxiliaries. Formation of the key hybrid alkyl Pd-radical intermediates is efficiently induced by visible light from alkyl iodides and Pd(0) complexes. Notably, this method requires no exogenous photosensitizers or external oxidants.