57221-80-4Relevant articles and documents
Synthesis of a highly fluorinated fatty acid analog
Buchanan, Gerald W.,Smits, Rufus,Munteanu, Elena
, p. 207 - 209 (2003)
A five-step synthesis of Z-11,11,12,12,13,13,14,14,15,15,16,16,17,17,18,18,18- heptadecafluoro-octadec-8-enoic acid is reported, starting from 1,8-octanediol and 1,1,2,2,3,3,4,4.5,5,6,6,7,7,8,8-heptadecafluoro-10-iododecane. The key step is a Wittig react
Total Synthesis of the Endocannabinoid Uptake Inhibitor Guineensine and SAR Studies
Bartholom?us, Ruben,Nicolussi, Simon,Baumann, Alice,Rau, Mark,Sim?o, Ana Catarina,Gertsch, Jürg,Altmann, Karl-Heinz
, p. 1590 - 1596 (2019/08/30)
Guineensine ((2E,4E,12E)-13-(benzo[d][1,3]dioxol-5-yl)-N-isobutyltrideca-2,4,12-trienamide) is a plant-derived natural product that inhibits reuptake of the endocannabinoid anandamide with sub-micromolar potency. We have established a highly efficient tot
NOVEL DIHYDROXYBENZENE DERIVATIVES AND ANTIPROTOZOAL AGENT COMPRISING SAME AS ACTIVE INGREDIENT
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, (2013/09/26)
Novel compounds below are useful for preventing or treating diseases caused by protozoans. At least one of a compound represented by Formula (I) (wherein, X represents a hydrogen atom or a halogen atom; R1 represents a hydrogen atom; R2 represents a hydrogen atom or a C1-7 alkyl group; R3 represents -CHO, -C(=O)R5, -COOR5 (wherein R5 represents a C1-7 alkyl group), -CH2OH or -COOH; and R4 represents a C1-16 alkyl group having one or more substituents on a terminal carbon atom and/or non-terminal carbon atom(s), a C2-16 alkenyl group having one or more substituents on a terminal carbon atom and/or non-terminal carbon atom(s), or a C2-16 alkynyl group having one or more substituents on a terminal carbon atom and/or non-terminal carbon atom(s)), an optical isomer thereof, and a pharmaceutically acceptable salt is used.