57266-61-2Relevant academic research and scientific papers
Alicyclic β- And γ-amino acids: Useful scaffolds for the stereocontrolled access to amino acid-based carbocyclic nucleoside analogs
Remete, Attila Márió,Kiss, Loránd
, (2019/01/21)
Stereocontrolled synthesis of some amino acid-based carbocyclic nucleoside analogs containing ring C=C bond has been performed on β- and γ-lactam basis. Key steps were N-arylation of readily available β- or γ-lactam-derived amino ester isomers and amino a
Synthesis of fluorinated piperidine and azepane β-amino acid derivatives
ábrahámi, Renáta Anita,Kiss, Loránd,Barrio, Pablo,Fül?p, Ferenc
, p. 7526 - 7535 (2016/11/11)
A convenient and robust stereocontrolled procedure has been developed for the synthesis of novel trifluoromethyl-containing piperidine and azepane β-amino ester stereoisomers. The synthesis started from readily available unsaturated bicyclic β-lactams and
Stereoselective synthesis of hydroxylated β-aminocyclohexanecarboxylic acids
Kiss, Loránd,Forró, Eniko,Martinek, Tamás A.,Bernáth, Gábor,De Kimpe, Norbert,Fül?p, Ferenc
, p. 5036 - 5043 (2008/09/21)
A simple synthetic approach has been developed for the regio- and diastereoselective synthesis of hydroxylated 2-aminocyclohexanecarboxylic acid stereoisomers from 1,4-cyclohexadiene by the reductive opening of appropriate epoxide intermediates derived from the corresponding bicyclic β-lactams. This method has been extended to the synthesis of these hydroxylated β-amino acids in enantiomerically pure form.
