57266-62-3Relevant articles and documents
Diversity-Oriented Stereocontrolled Synthesis of Some Piperidine- And Azepane-Based Fluorine-Containing β-Amino Acid Derivatives
Nonn, Melinda,Kara, Dominika,Ouchakour, Lamiaa,Forró, Eniko,Haukka, Matti,Kiss, Loránd
, p. 1163 - 1173 (2020/12/28)
Structural diversity-oriented synthesis of some azaheterocyclic β-amino acid derivatives has been accomplished by selective functionalization of readily available cyclodienes. The stereocontrolled synthetic concept was based on the oxidative ring cleavage of unsaturated cyclic β-amino acids derived from cycloalkadiene, followed by ring closing with double reductive amination, which furnished some conformationally restricted β-amino acid derivatives with a piperidine or azepane core.