5728-87-0Relevant academic research and scientific papers
Palladium-catalyzed decarboxylative aminocarbonylation with alkynoic acid and tertiary amine for the synthesis of alkynyl amide
Idris, Muhammad Aliyu,Kim, Myungjin,Kim, Jeung Gon,Lee, Sunwoo
, p. 4130 - 4137 (2019)
We developed a method for the synthesis of alkynyl amides via the carbonylation of alkynoic acids and C-N activation of tertiary amines. The reaction of alkynoic acid and tertiary amine with carbon monoxide using a palladium catalyst in the presence of oxygen, KI, and K3PO4, gave the desired alkynyl amides in good yields.
