57287-86-2Relevant articles and documents
Rapid microwave-assisted deprotection of N-Cbz and N-Bn derivatives
Daga, Maria Caterina,Taddei, Maurizio,Varchi, Greta
, p. 5191 - 5194 (2007/10/03)
Catalytic-transfer hydrogenation in iso-propanol under microwave irradiation has been performed to rapidly deprotect N-Cbz and N-Bn derivatives. The method is particularly suitable for the synthesis of short peptides and can also be carried out on supported molecules. The rapid cleavage of chiral molecules derived from (S)-1-phenylethylamine can be very useful for asymmetric synthesis of nitrogen containing compounds.