57289-77-7 Usage
Description
9-oxa-2-azaspiro[5.5]undecane, also known as PBOX, is an organic compound characterized by its unique spirocyclic structure, featuring an eight-membered oxygen-containing ring fused to a six-membered nitrogen-containing ring. This structural complexity endows PBOX with a range of biological activities, making it a compound of interest in the pharmaceutical industry.
Uses
Used in Pharmaceutical Development:
9-oxa-2-azaspiro[5.5]undecane is used as a potential anticancer agent for its demonstrated ability to inhibit the growth of cancer cells. Its unique structure allows it to interact with cellular targets in ways that traditional compounds may not, offering a new avenue for cancer treatment.
Used in Oncology Research:
In the field of oncology, 9-oxa-2-azaspiro[5.5]undecane is used as a research compound to explore its potential in inducing apoptosis, or programmed cell death, in cancer cells. This property is crucial for the development of drugs that can effectively target and eliminate cancerous cells without harming healthy tissue.
Used in Combination Therapy:
9-oxa-2-azaspiro[5.5]undecane is also being studied for its potential use in combination therapy, where it can be paired with existing treatments to enhance their effectiveness. This approach can be particularly beneficial in overcoming drug resistance and improving patient outcomes in cancer treatment.
Used in Neurodegenerative Disease Treatment:
Beyond oncology, 9-oxa-2-azaspiro[5.5]undecane has been investigated for its potential application in treating neurodegenerative diseases. Its unique structure and biological activity may offer new insights into the treatment of conditions such as Alzheimer's and Parkinson's diseases.
Used as an Anti-Inflammatory Agent:
In addition to its anticancer properties, 9-oxa-2-azaspiro[5.5]undecane has shown promise as an anti-inflammatory agent. This application could be beneficial in the treatment of various inflammatory conditions, where reducing inflammation is key to managing symptoms and preventing disease progression.
Check Digit Verification of cas no
The CAS Registry Mumber 57289-77-7 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,7,2,8 and 9 respectively; the second part has 2 digits, 7 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 57289-77:
(7*5)+(6*7)+(5*2)+(4*8)+(3*9)+(2*7)+(1*7)=167
167 % 10 = 7
So 57289-77-7 is a valid CAS Registry Number.
InChI:InChI=1/C9H17NO/c1-2-9(8-10-5-1)3-6-11-7-4-9/h10H,1-8H2
57289-77-7Relevant articles and documents
HIV integrase inhibitors
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Page/Page column 18, (2010/02/14)
Compounds of the present disclosure are spirocycle-substituted pyrimidinecarboxamides. Also disclosed are pharmaceutical compositions comprising the compounds, and methods of using the compounds. The compounds are useful for treating HIV infection and AIDS.
