5729-54-4

Basic information

• Product Name: 5-cyclohexyl-
• Synonyms: 5-Cyclohexyl-1-penten;pent-4-enyl-cyclohexane;Pent-4-enyl-cyclohexan
• CAS NO: 5729-54-4
• Molecular Formula: C11H20
• Molecular Weight: 152.28
• Mol File: 5729-54-4.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 5-cyclohexyl-(CAS DataBase Reference)
• NIST Chemistry Reference: 5-cyclohexyl-(5729-54-4)
• EPA Substance Registry System: 5-cyclohexyl-(5729-54-4)

Safety Data

• Hazardous Substances Data: 5729-54-4(Hazardous Substances Data)

Upstream product

• 106-95-6 allyl bromide 
• 1119-51-3 bromopentene 
• 931-50-0 cyclohexylmagnesium bromide 
• 7103-09-5 4-but-1-enylmagnesium bromide 
• 70869-86-2 cyclohexylmethyl trifluoromethanesulfonate 

Downstream Products

• 4292-92-6 n-pentylcyclohexane 
• 538-68-1 pentylbenzene 

Relevant articles and documents

Total syntheses of all tri-oxygenated 16-phytoprostane classes: Via a common precursor constructed by oxidative cyclization and alkyl-alkyl coupling reactions as the key steps

A unified strategy for the total synthesis of the methyl esters of all phytoprostane (PhytoP) classes bearing two ring-oxygen atoms based on an orthogonally protected common precursor is described. Racemic 16-F1t-, 16-E1-PhytoP and their C-16 epimers, which also occur as racemates in Nature, were successfully obtained. The first total synthesis of very sensitive 16-D1t-PhytoP succeeded, however, it quickly isomerized to more stable, but so far also unknown Δ13-16-D1t-PhytoP, which may serve as a more reliable biomarker for D-type PhytoP. The dioxygenated cyclopentane ring carrying the ω-chain with the oxygen functionality in the 16-position was approached by a radical oxidative cyclization mediated by ferrocenium hexafluorophosphate and TEMPO. The α-chain was introduced by a new copper-catalyzed alkyl-alkyl coupling of a 6-heptenyl Grignard reagent with a functionalized cyclopentylmethyl triflate.