572916-18-8

Basic information

• Product Name: (2S,4S)-2-[(R)-(hydroxy)(3,4-methylenedioxyphenyl)methyl]-5-trityloxy-4-pentanolide
• Synonyms: (2S,4S)-2-[(R)-(hydroxy)(3,4-methylenedioxyphenyl)methyl]-5-trityloxy-4-pentanolide
• CAS NO: 572916-18-8
• Molecular Weight: 508.571
• Mol File: 572916-18-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (2S,4S)-2-[(R)-(hydroxy)(3,4-methylenedioxyphenyl)methyl]-5-trityloxy-4-pentanolide(CAS DataBase Reference)
• NIST Chemistry Reference: (2S,4S)-2-[(R)-(hydroxy)(3,4-methylenedioxyphenyl)methyl]-5-trityloxy-4-pentanolide(572916-18-8)
• EPA Substance Registry System: (2S,4S)-2-[(R)-(hydroxy)(3,4-methylenedioxyphenyl)methyl]-5-trityloxy-4-pentanolide(572916-18-8)

Safety Data

• Hazardous Substances Data: 572916-18-8(Hazardous Substances Data)

Upstream product

• 120-57-0 piperonal 
• 73968-62-4 (5S)-5-[(trityloxy)methyl]tetrahydro-2-furanone 

Downstream Products

• 58262-61-6 (1R,2S,5S,6S)-4-hydroxy-2,6-bis(3,4-methylenedioxyphenyl)-3,7-dioxabicyclo[3.3.0]octane 
• 105661-99-2 (+)-aptosimon 
• 572916-25-7 (2S,4S)-2-[(R)-(3,4-methylenedioxyphenyl)(triisopropylsilyloxy)methyl]-5-trityloxy-4-pentanolide 

Relevant articles and documents

Synthesis of (+)-aptosimon, a 4-oxofurofuran lignan, by erythro selective aldol condensation and stereoconvergent cyclization as the key reactions

The 4-oxofurofuran lignan, (+)-aptosimon (1), was synthesized from γ-butyrolactone (9). To construct the two benzylic chiral center of (+)-aptosimon (1), highly erythro selective aldol condensation and stereoconvergent SN1 intramolecular cyclization were used as the key reactions.