57319-72-9Relevant academic research and scientific papers
Design and structure-activity relationships anticandidosic of diazaheteroaryl functionalized by Micha?l acceptors
Aboudramane, Kone,Doumade, Zon,Drissa, Sissouma,Jean-Paul, N'Guessan D.,Mahama, Ouattara,Mamidou, Koné Witabouna,Songuigama, Coulibaly
, p. 117 - 133 (2022/02/14)
Benzimidazole and imidazopyridine heterocycles associated with Micha?l acceptors have shown strong anticandidosic potential in our previous work. After a decade of research, we have designed, synthesized and evaluated the anticandidosic activities of seve
Benzimidazole derivatives related to 2,3-acrylonitriles, benzimidazo[1,2-a]quinolines and fluorenes: Synthesis, antitumor evaluation in vitro and crystal structure determination
Hranjec, Marijana,Pavlovi?, Gordana,Marjanovi?, Marko,Kralj, Marijeta,Karminski-Zamola, Grace
experimental part, p. 2405 - 2417 (2010/07/05)
A synthesis and biological evaluation of new benzimidazole derivatives, related to 2,3-disubstituted acrylonitriles, benzimidazo[1,2-a]quinoline-6-carbonitriles and heteroaromatic fluorenes was described. The molecular and crystal structures of three comp
Anhydrous zinc chloride catalysis in carbonyl-methylene condensations: Synthesis of arylidene acetonitriles and arylidene heterocycles
Rao, P. Shanthan,Venkataratnam, R. V.
, p. 484 - 486 (2007/10/02)
Anhydrous zinc chloride has been found to be an efficient catalyst in carbonyl-methylene condensation reactions.The synthesis of arylidene acetonitriles (6a-g, 7a-g) and arylidene heterocycles (8a-e, 9a-e) have been accomplished in high yields and good purity.
NITRILES IN HETEROCYCLIC SYNTHESIS: NOVEL SYNTHESES OF BENZOIMIDAZOPYRIMIDINES AND BENZOIMIDAZOPYRIDINE DERIVATIVES
Hammad, Mahmoud Ahmed,Nawwar, Galal Abdel Moien,Elgemeie, Galal Eldin Hamza,Elnagdi, Mohamed Hilmy
, p. 2177 - 2181 (2007/10/02)
Novel syntheses of benzoimidazopyrimidines and benzoimidazopyridine derivatives utilising 2-(2-benzimidazolyl)acetonitrile as starting component is reported.
Reactions of cyanomethylbenzimidazoles. Part II. Reaction of cyanomethylbenzimidazoles with aldehydes methylketones and nitroso compounds.
Sawlewicz,Milczarska,Manowska
, p. 187 - 201 (2007/10/09)
Position of CH2CN group in the benzimidazole system determines the activity of hydrogen atoms of CH2 group in condensation reactions. Some of the obtained compounds show high tuberculostatic activity.
